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Utility of an "allosteric site-impaired" M2 muscarinic acetylcholine receptor as a novel construct for validating mechanisms of action of synthetic and putative endogenous allosteric modulators
Ee Von Moo, Patrick M. Sexton, Arthur Christopoulos and Celine Valant

Molecular Pharmacology September 13, 2018, mol.118.112490; DOI: https://doi.org/10.1124/mol.118.112490
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Effects of HCN Channels in the Rostral Ventrolateral Medulla Contribute to the Cardiovascular Effects of Propofol
Zhiqiang Hu, Zhilin Wu, Jie Gao, Qi Jia, Na Li, Yeling Ouyang, Shanglong Yao and Xiangdong Chen

Molecular Pharmacology September 7, 2018, mol.118.111898; DOI: https://doi.org/10.1124/mol.118.111898
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Molecular characterization of binding loop E in the nematode cys-loop GABA receptor
Ariel Kwaka, Mohammad H Khatami, Joshua Foster, Everett Cochrane, Sarah A Habibi, Hendrick W de Haan and Sean G Forrester

Molecular Pharmacology September 7, 2018, mol.118.112821; DOI: https://doi.org/10.1124/mol.118.112821
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Activation of Caenorhabditis elegans levamisole-sensitive and mammalian nicotinic receptors by the antiparasitic bephenium
Ornella Turani, Guillermina Hernando, Jeremias Corradi and Cecilia Bouzat

Molecular Pharmacology September 6, 2018, mol.118.113357; DOI: https://doi.org/10.1124/mol.118.113357
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Chemoproteomic discovery of a ritanserin-targeted kinase network mediating apoptotic cell death of lung tumor cells
Sean T Campbell, Caroline E Franks, Adam L Borne, Myungsun Shin, Liuzhi Zhang and Ku-Lung Hsu

Molecular Pharmacology August 29, 2018, mol.118.113001; DOI: https://doi.org/10.1124/mol.118.113001
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The novel activity of carbamazepine as an activation modulator extends from NaV1.7 mutations to the NaV1.8-S242T mutant channel from a patient with painful diabetic neuropathy
Chongyang Han, Andreas C Themistocleous, Mark Estacion, Fadia B Dib-Hajj, Iulia Blesneac, Lawrence Macala, Carl Fratter, David L Bennett, Stephen G. Waxman and Sulayman D. Dib-Hajj

Molecular Pharmacology August 22, 2018, mol.118.113076; DOI: https://doi.org/10.1124/mol.118.113076

About Molecular Pharmacology

Molecular Pharmacology publishes findings derived from the application of innovative structural biology, biochemistry, biophysics, physiology, genetics, and molecular biology to basic pharmacological problems that provide mechanistic insights that are broadly important for the fields of pharmacology and toxicology. Relevant topics include:

Molecular Signaling / Mechanism of Drug Action
Chemical Biology / Drug Discovery
Structure of Drug-Receptor Complex
Systems Analysis of Drug Action
Drug Transport / Metabolism

For an alternate route to this Journal use this URL: http://intl-molpharm.aspetjournals.org

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