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Molecular Pharmacology, Vol 2, 86-89, Copyright © 1966 by the American Society for Pharmacology and Experimental Therapeutics

Further Studies on the Solubilities of Xenon and Cyclopropane in Blood and Protein Solutions

C. A. MUEHLBAECHER 1, F. L. DEBON 1, and R. M. FEATHERSTONE 1

1 Department of Pharmacology and Anesthesiology, School of Medicine, San Francisco Medical Center, University of California, San Francisco, California

The solubility of xenon and krypton in whole blood and plasma has been measured chromatographically and shown to vary from species to species. Some physical-chemical parameters of another nonhydrogen bonding gas—protein system (cyclopropane—serum albumin) have been studied, and no changes in the degree of protein—gas interaction could be observed with changes in pH, temperature, or ionic strength of the solutions.

Submitted on October 25, 1965




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