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Molecular Pharmacology, Vol 3, 495-496, Copyright © 1967 by the American Society for Pharmacology and Experimental Therapeutics

Effects of Vitamins K1 and K3 on Adenosine Nucleotide Content of Rat Tissues

P. GÖRÖG 1 and I. B. KOVÁCS 1

1 Pharmacological Department, United Pharmaceutical Works, Budapest, Hungary

Vitamin K3 treatment considerably reduces the ATP content and ATP/ADP ratio in liver and heart in rats. Vitamin K1 decreases the ATP level only in the liver. Correlations may exist between the uncoupling activity measured in vivo and the anti-inflammatory action of vitamins K.

Submitted on May 9, 1967






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