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Molecular Pharmacology, Vol 4, 196-199, Copyright © 1968 by the American Society for Pharmacology and Experimental Therapeutics

Release of Catecholamines from Isolated Adrenal Chromaffin Granules by Endogenous ATP

A. M. POISNER 1 and J. M. TRIFARÓ 1

1 Department of Pharmacology, Albert Einstein College of Medicine, New York, New York 10461

By the use of ATP-regenerating systems it can be shown that the ATP leaking from adrenal chromaffin granules in vitro produces the same effects on these granules as does the addition of exogenous ATP, i.e., release of catecholamines and change in light-scattering properties.

Submitted on November 6, 1967






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Copyright © 1968 by the American Society for Pharmacology and Experimental Therapeutics