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Erratum for Hall, Mol Pharmacol 58 (6) 1412-1423.
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Vol. 59, Issue 1, 161-161, January 2001

Molecular Pharmacology 58: 1412

Correction to "Modeling the functional effects of allosteric modulators at pharmacological receptors: An extension of the two-state model of receptor activation"

  In the above article [Hall D (2000) Mol Pharmacol 58:1412-1423], typographical errors were made in several equations. We apologize for any confusion or inconvenience caused by these errors.   The inequality on page 1419 should appear as
(&dgr;>(1+&agr;L+&ggr;M[<UP>B</UP>])/&agr;&ggr;(1+L+M[<UP>B</UP>]))
Equation 3 (page 1421) should be
<FR><NU>[<UP>A</UP>]<SUB><UP>Bound</UP></SUB></NU><DE>[<UP>R</UP>]<SUB><UP>T</UP></SUB></DE></FR>=<FR><NU>[<UP>A</UP>]</NU><DE><FR><NU>1+L+M[<UP>B</UP>](1+&bgr;L)</NU><DE>K(1+&agr;L+&ggr;M[<UP>B</UP>](1+&agr;&bgr;&dgr;L))</DE></FR>+[<UP>A</UP>]</DE></FR>
The first equation in the second column of page 1421 should be
<FR><NU>1</NU><DE>2</DE></FR><FENCE><FR><NU>K[<UP>A</UP>](1+&agr;L)</NU><DE>1+L+K[<UP>A</UP>](1+&agr;L)</DE></FR>+<FR><NU>&ggr;K[<UP>A</UP>](1+&agr;&bgr;&dgr;L)</NU><DE>1+&bgr;L+&ggr;K[<UP>A</UP>](1+&agr;&bgr;&dgr;L)</DE></FR></FENCE>=<FR><NU>[<UP>A</UP>]</NU><DE><FR><NU>1+L+M[<UP>B</UP>]<SUB>50</SUB>(1+&bgr;L)</NU><DE>K(1+&agr;L+&ggr;M[<UP>B</UP>]<SUB>50</SUB>(1+&agr;&bgr;&dgr;L))</DE></FR>+[<UP>A</UP>]</DE></FR>





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