Research ArticleArticle
Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185
Yu-Ching Lee
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Nai-Wan Hsiao
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Tien-Sheng Tseng
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Wang-Chuan Chen
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Hui-Hsiung Lin
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Sy-Jye Leu
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Ei-Wen Yang
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Keng-Chang Tsai
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
MolPharm articles become freely available 12 months after publication, and remain freely available for 5 years.Non-open access articles that fall outside this five year window are available only to institutional subscribers and current ASPET members, or through the article purchase feature at the bottom of the page.
|
Log in using your username and password
Purchase access
You may purchase access to this article. This will require you to create an account if you don't already have one.
In this issue
Research ArticleArticle
Tyrosinase Inhibitor Discovery and Molecular Docking
Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
Molecular Pharmacology February 1, 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185
Research ArticleArticle
Tyrosinase Inhibitor Discovery and Molecular Docking
Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
Molecular Pharmacology February 1, 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185
Jump to section
Related Articles
Cited By...
More in this TOC Section
Similar Articles
Advertisement