On the Mechanism of Action of 9-O-Arylalkyloxime Derivatives of 6-O-Mycaminosyltylonolide, a New Class of 16-Membered Macrolide Antibiotics
Mol Pharmacol Karahalios et al.
70: 1271
Data Supplement
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Data Supplement
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In Scheme 3, symbols I, A and C represent tylosin, ligand A and Pi ribosomal complex, respectively. In this kinetic scheme two competitive reactions take place simultaneously; the reaction of complex C with tylosin (I), and the reaction of complex C with ligand A (one of the three new 16-membered macrolides)...