A Three-Dimensional Quantitative Structure-Activity Relationship Study of the Inhibition of the ATPase Activity and the Strand Passing Catalytic Activity of Topoisomerase II by Substituted Purine Analogs

Data Supplement

Files in this Data Supplement:

• Data Supplement - Supplement 1. Mass spectrometric identification and HPLC purity of NSC purine compounds.
• Data Supplement - Supplement 2. Table. Experimental OC50 values for inhibition of topoisemarase II alpha ATPase activity…
• Data Supplement - Supplement 3. Figure Legends.
• Data Supplement - Supplement 4. Figure 1. The structures of all the purine and purine-like compounds used in this study.
• Data Supplement - Supplement 5. Figure 2. The inhibition of the ATPase activity of topoisomerase ll alpha…
• Data Supplement - Supplement 6. Figure 3. Effect of 40 purine or purine like compounds on the level of topoisomerase ll alpha…