Table of Contents

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- B Badio and
- J W Daly
Epibatidine, a potent analgetic and nicotinic agonist.
Mol Pharmacol April 1994 45:563-569
- Abstract
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- L Prézeau,
- J Carrette,
- B Helpap,
- K Curry,
- J P Pin,
- and J Bockaert
Pharmacological characterization of metabotropic glutamate receptors in several types of brain cells in primary cultures.
Mol Pharmacol April 1994 45:570-577
- Abstract
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- R Seifert,
- A Hagelüken,
- A Höer,
- D Höer,
- L Grünbaum,
- S Offermanns,
- I Schwaner,
- V Zingel,
- W Schunack,
- and G Schultz
The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes.
Mol Pharmacol April 1994 45:578-586
- Abstract
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- S F Law,
- S Zaina,
- R Sweet,
- K Yasuda,
- G I Bell,
- J Stadel,
- and T Reisine
Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation.
Mol Pharmacol April 1994 45:587-590
- Abstract
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- T A Esbenshade,
- T L Theroux,
- and K P Minneman
Increased voltage-dependent calcium influx produced by alpha 1B-adrenergic receptor activation in rat medullary thyroid carcinoma 6-23 cells.
Mol Pharmacol April 1994 45:591-598
- Abstract
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- S S Poirot,
- C Escrieut,
- M Dufresne,
- J Martinez,
- M Bouisson,
- N Vaysse,
- and D Fourmy
Photoaffinity labeling of rat pancreatic cholecystokinin type A receptor antagonist binding sites demonstrates the presence of a truncated cholecystokinin type A receptor.
Mol Pharmacol April 1994 45:599-607
- Abstract
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- K M Kim,
- S F Kingsmore,
- H Han,
- T L Yang-Feng,
- N Godinot,
- M F Seldin,
- M G Caron,
- and B Giros
Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes.
Mol Pharmacol April 1994 45:608-617
- Abstract
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- X J Hu and
- M K Ticku
Chronic benzodiazepine agonist treatment produces functional uncoupling of the gamma-aminobutyric acid-benzodiazepine receptor ionophore complex in cortical neurons.
Mol Pharmacol April 1994 45:618-625
- Abstract
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- M V Catania,
- H De Socarraz,
- J B Penney,
- and A B Young
Metabotropic glutamate receptor heterogeneity in rat brain.
Mol Pharmacol April 1994 45:626-636
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- B T Harris,
- M E Charlton,
- E Costa,
- and D R Grayson
Quantitative changes in alpha 1 and alpha 5 gamma-aminobutyric acid type A receptor subunit mRNAs and proteins after a single treatment of cerebellar granule neurons with N-methyl-D-aspartate.
Mol Pharmacol April 1994 45:637-648
- Abstract
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- F A Fornari,
- J K Randolph,
- J C Yalowich,
- M K Ritke,
- and D A Gewirtz
Interference by doxorubicin with DNA unwinding in MCF-7 breast tumor cells.
Mol Pharmacol April 1994 45:649-656
- Abstract
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- T J Zhao,
- T H Chiu,
- and H C Rosenberg
Reduced expression of gamma-aminobutyric acid type A/benzodiazepine receptor gamma 2 and alpha 5 subunit mRNAs in brain regions of flurazepam-treated rats.
Mol Pharmacol April 1994 45:657-663
- Abstract
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- C H Chichester,
- A R Buckpitt,
- A Chang,
- and C G Plopper
Metabolism and cytotoxicity of naphthalene and its metabolites in isolated murine Clara cells.
Mol Pharmacol April 1994 45:664-672
- Abstract
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- I Posner,
- M Engel,
- A Gazit,
- and A Levitzki
Kinetics of inhibition by tyrphostins of the tyrosine kinase activity of the epidermal growth factor receptor and analysis by a new computer program.
Mol Pharmacol April 1994 45:673-683
- Abstract
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- E Falck-Pedersen,
- M Heinflink,
- M Alvira,
- D R Nussenzveig,
- and M C Gershengorn
Expression of thyrotropin-releasing hormone receptors by adenovirus-mediated gene transfer reveals that thyrotropin-releasing hormone desensitization is cell specific.
Mol Pharmacol April 1994 45:684-689
- Abstract
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- R R Huang,
- H Yu,
- C D Strader,
- and T M Fong
Localization of the ligand binding site of the neurokinin-1 receptor: interpretation of chimeric mutations and single-residue substitutions.
Mol Pharmacol April 1994 45:690-695
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- M G Eason,
- M T Jacinto,
- and S B Liggett
Contribution of ligand structure to activation of alpha 2-adrenergic receptor subtype coupling to Gs.
Mol Pharmacol April 1994 45:696-702
- Abstract
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- C Forray,
- J A Bard,
- J M Wetzel,
- G Chiu,
- E Shapiro,
- R Tang,
- H Lepor,
- P R Hartig,
- R L Weinshank,
- and T A Branchek
The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype.
Mol Pharmacol April 1994 45:703-708
- Abstract
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- J Proska and
- S Tucek
Mechanisms of steric and cooperative actions of alcuronium on cardiac muscarinic acetylcholine receptors.
Mol Pharmacol April 1994 45:709-717
- Abstract
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- F J Thomson,
- L Perkins,
- D Ahern,
- and M Clark
Identification and characterization of a lysophosphatidic acid receptor.
Mol Pharmacol April 1994 45:718-723
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- T Tanaka,
- E Tsukuda,
- M Nozawa,
- H Nonaka,
- T Ohno,
- H Kase,
- K Yamada,
- and Y Matsuda
RES-701-1, a novel, potent, endothelin type B receptor-selective antagonist of microbial origin.
Mol Pharmacol April 1994 45:724-730
- Abstract
- Full Text (PDF)
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- G F Wilkinson,
- J R Purkiss,
- and M R Boarder
Differential heterologous and homologous desensitization of two receptors for ATP (P2y purinoceptors and nucleotide receptors) coexisting on endothelial cells.
Mol Pharmacol April 1994 45:731-736
- Abstract
- Full Text (PDF)
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- V Calderaro,
- C Parrillo,
- M L Balestrieri,
- A Giovane,
- A Filippelli,
- and F Rossi
Docosahexaenoic acid and signaling pathways in rabbit colon.
Mol Pharmacol April 1994 45:737-746
- Abstract
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- J Church,
- E J Fletcher,
- K Abdel-Hamid,
- and J F MacDonald
Loperamide blocks high-voltage-activated calcium channels and N-methyl-D-aspartate-evoked responses in rat and mouse cultured hippocampal pyramidal neurons.
Mol Pharmacol April 1994 45:747-757
- Abstract
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- G A Stafford,
- R E Oswald,
- and G A Weiland
The beta subunit of neuronal nicotinic acetylcholine receptors is a determinant of the affinity for substance P inhibition.
Mol Pharmacol April 1994 45:758-762
- Abstract
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- W D Stein,
- C Cardarelli,
- I Pastan,
- and M M Gottesman
Kinetic evidence suggesting that the multidrug transporter differentially handles influx and efflux of its substrates.
Mol Pharmacol April 1994 45:763-772
- Abstract
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- U S Rao and
- G A Scarborough
Direct demonstration of high affinity interactions of immunosuppressant drugs with the drug binding site of the human P-glycoprotein.
Mol Pharmacol April 1994 45:773-776
- Abstract
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- R Agbaria,
- C A Mullen,
- N R Hartman,
- D A Cooney,
- Z Hao,
- R M Blaese,
- and D G Johns
Effects of IMP dehydrogenase inhibitors on the phosphorylation of ganciclovir in MOLT-4 cells before and after herpes simplex virus thymidine kinase gene transduction.
Mol Pharmacol April 1994 45:777-782
- Abstract
- Full Text (PDF)
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- M S Rhee,
- J Galivan,
- J E Wright,
- and A Rosowsky
Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
Mol Pharmacol April 1994 45:783-791
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- S Pötsch,
- H Drechsler,
- B Liermann,
- A Gräslund,
- and G Lassmann
p-Alkoxyphenols, a new class of inhibitors of mammalian R2 ribonucleotide reductase: possible candidates for antimelanotic drugs.
Mol Pharmacol April 1994 45:792-796
- Abstract
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- N S Kolb,
- L A Hunsaker,
- and D L Vander Jagt
Aldose reductase-catalyzed reduction of acrolein: implications in cyclophosphamide toxicity.
Mol Pharmacol April 1994 45:797-801
- Abstract
- Full Text (PDF)

Epibatidine, a potent analgetic and nicotinic agonist.

Pharmacological characterization of metabotropic glutamate receptors in several types of brain cells in primary cultures.

The H1 receptor agonist 2-(3-chlorophenyl)histamine activates Gi proteins in HL-60 cells through a mechanism that is independent of known histamine receptor subtypes.

Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation.

Increased voltage-dependent calcium influx produced by alpha 1B-adrenergic receptor activation in rat medullary thyroid carcinoma 6-23 cells.

Photoaffinity labeling of rat pancreatic cholecystokinin type A receptor antagonist binding sites demonstrates the presence of a truncated cholecystokinin type A receptor.

Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes.

Chronic benzodiazepine agonist treatment produces functional uncoupling of the gamma-aminobutyric acid-benzodiazepine receptor ionophore complex in cortical neurons.

Metabotropic glutamate receptor heterogeneity in rat brain.

Quantitative changes in alpha 1 and alpha 5 gamma-aminobutyric acid type A receptor subunit mRNAs and proteins after a single treatment of cerebellar granule neurons with N-methyl-D-aspartate.

Interference by doxorubicin with DNA unwinding in MCF-7 breast tumor cells.

Reduced expression of gamma-aminobutyric acid type A/benzodiazepine receptor gamma 2 and alpha 5 subunit mRNAs in brain regions of flurazepam-treated rats.

Metabolism and cytotoxicity of naphthalene and its metabolites in isolated murine Clara cells.

Kinetics of inhibition by tyrphostins of the tyrosine kinase activity of the epidermal growth factor receptor and analysis by a new computer program.

Expression of thyrotropin-releasing hormone receptors by adenovirus-mediated gene transfer reveals that thyrotropin-releasing hormone desensitization is cell specific.

Localization of the ligand binding site of the neurokinin-1 receptor: interpretation of chimeric mutations and single-residue substitutions.

Contribution of ligand structure to activation of alpha 2-adrenergic receptor subtype coupling to Gs.

The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype.

Mechanisms of steric and cooperative actions of alcuronium on cardiac muscarinic acetylcholine receptors.

Identification and characterization of a lysophosphatidic acid receptor.

RES-701-1, a novel, potent, endothelin type B receptor-selective antagonist of microbial origin.

Differential heterologous and homologous desensitization of two receptors for ATP (P2y purinoceptors and nucleotide receptors) coexisting on endothelial cells.

Docosahexaenoic acid and signaling pathways in rabbit colon.

Loperamide blocks high-voltage-activated calcium channels and N-methyl-D-aspartate-evoked responses in rat and mouse cultured hippocampal pyramidal neurons.

The beta subunit of neuronal nicotinic acetylcholine receptors is a determinant of the affinity for substance P inhibition.

Kinetic evidence suggesting that the multidrug transporter differentially handles influx and efflux of its substrates.

Direct demonstration of high affinity interactions of immunosuppressant drugs with the drug binding site of the human P-glycoprotein.

Effects of IMP dehydrogenase inhibitors on the phosphorylation of ganciclovir in MOLT-4 cells before and after herpes simplex virus thymidine kinase gene transduction.

Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.

p-Alkoxyphenols, a new class of inhibitors of mammalian R2 ribonucleotide reductase: possible candidates for antimelanotic drugs.

Aldose reductase-catalyzed reduction of acrolein: implications in cyclophosphamide toxicity.

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