Table of Contents

Articles

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  Antimitogenic Effects of Trapidil In Coronary Artery Smooth Muscle Cells by Direct Activation of Protein Kinase A

  Detlef Bönisch, Artur-Aron Weber, Michael Wittpoth, Michael Osinski and Karsten Schrör

  Molecular Pharmacology August 1998, 54 (2) 241-248; DOI: https://doi.org/10.1124/mol.54.2.241
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  Selective Activation of a Chimeric G_i1/G_sG Protein α Subunit by the Human IP Prostanoid Receptor: Analysis Using Agonist Stimulation of High Affinity GTPase Activity and [³⁵S]Guanosine-5′-O-(3-thio)triphosphate Binding

  Chee Wai Fong, Daljit S. Bahia, Stephen Rees and Graeme Milligan

  Molecular Pharmacology August 1998, 54 (2) 249-257; DOI: https://doi.org/10.1124/mol.54.2.249
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  Expressional Down-Regulation of Neuronal-Type Nitric Oxide Synthase I by Glucocorticoids in N1E-115 Neuroblastoma Cells

  Petra M. Schwarz, Birgit Gierten, Jean-Paul Boissel and Ulrich Förstermann

  Molecular Pharmacology August 1998, 54 (2) 258-263; DOI: https://doi.org/10.1124/mol.54.2.258
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  Histamine Induces Nuclear Factor of Activated T Cell-Mediated Transcription and Cyclosporin A-Sensitive Interleukin-8 mRNA Expression in Human Umbilical Vein Endothelial Cells

  Valerie Boss, Xiaofei Wang, Lacie F. Koppelman, Kaiming Xu and T. J. Murphy

  Molecular Pharmacology August 1998, 54 (2) 264-272; DOI: https://doi.org/10.1124/mol.54.2.264
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  Down-Regulation of Cytochrome P450 mRNAs and Proteins in Mice Lacking a Functional NOS2 Gene

  Marion B. Sewer, Thomas B. Barclay and Edward T. Morgan

  Molecular Pharmacology August 1998, 54 (2) 273-279; DOI: https://doi.org/10.1124/mol.54.2.273
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  Highly Potent Synthetic Polyamides, Bisdistamycins, and Lexitropsins as Inhibitors of Human Immunodeficiency Virus Type 1 Integrase

  Nouri Neamati, Abhijit Mazumder, Sanjay Sunder, Joshua M. Owen, Manju Tandon, J. William Lown and Yves Pommier

  Molecular Pharmacology August 1998, 54 (2) 280-290; DOI: https://doi.org/10.1124/mol.54.2.280
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  Human Immunodeficiency Virus Type 1 Reverse Transcriptase Expressing the K70E Mutation Exhibits a Decrease in Specific Activity and Processivity

  Michael D. Miller, Patrick D. Lamy, Michael D. Fuller, Andrew S. Mulato, Nicolas A. Margot, Tomas Cihlar and Julie M. Cherrington

  Molecular Pharmacology August 1998, 54 (2) 291-297; DOI: https://doi.org/10.1124/mol.54.2.291
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  Overexpression of Stably Transfected Human Glutathione S-Transferase P1–1 Protects against DNA Damage by Benzo[a]pyrene Diol-Epoxide in Human T47D Cells

  Wanda R. Fields, Charles S. Morrow, Amanda J. Doss, Kathrin Sundberg, Bengt Jernström and Alan J. Townsend

  Molecular Pharmacology August 1998, 54 (2) 298-304; DOI: https://doi.org/10.1124/mol.54.2.298
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  Neuronal Nitric Oxide Synthase Isoforms α and μ Are Closely Related Calpain-Sensitive Proteins

  Romuald Lainé and Paul R. Ortiz de Montellano

  Molecular Pharmacology August 1998, 54 (2) 305-312; DOI: https://doi.org/10.1124/mol.54.2.305
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  The Involvement of Aryl Hydrocarbon Receptor in the Activation of Transforming Growth Factor-β and Apoptosis

  Hani Zaher, Pedro M. Fernandez-Salguero, John Letterio, M. Saeed Sheikh, Albert J. Fornace, Anita B. Roberts and Frank J. Gonzalez

  Molecular Pharmacology August 1998, 54 (2) 313-321; DOI: https://doi.org/10.1124/mol.54.2.313
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  Rat α3/β4 Subtype of Neuronal Nicotinic Acetylcholine Receptor Stably Expressed in a Transfected Cell Line: Pharmacology of Ligand Binding and Function

  Yingxian Xiao, Erin L. Meyer, Jessica M. Thompson, Alexander Surin, Jarda Wroblewski and Kenneth J. Kellar

  Molecular Pharmacology August 1998, 54 (2) 322-333; DOI: https://doi.org/10.1124/mol.54.2.322
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  Involvement of the Mismatch Repair System in Temozolomide-Induced Apoptosis

  Stefania D’Atri, Lucio Tentori, Pedro Miguel Lacal, Grazia Graziani, Elena Pagani, Elena Benincasa, Giovanna Zambruno, Enzo Bonmassar and Josef Jiricny

  Molecular Pharmacology August 1998, 54 (2) 334-341; DOI: https://doi.org/10.1124/mol.54.2.334
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  Human Neurons Express the Polyspecific Cation Transporter hOCT2, Which Translocates Monoamine Neurotransmitters, Amantadine, and Memantine

  Andreas E. Busch, Ulrich Karbach, Dagmar Miska, Valentin Gorboulev, Aida Akhoundova, Christopher Volk, Petra Arndt, Jochen C. Ulzheimer, Mark S. Sonders, Carmen Baumann, Siegfried Waldegger, Florian Lang and Hermann Koepsell

  Molecular Pharmacology August 1998, 54 (2) 342-352; DOI: https://doi.org/10.1124/mol.54.2.342
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  Mechanisms of Action of 2,3-Dimercaptopropane-1-sulfonate and the Transport, Disposition, and Toxicity of Inorganic Mercury in Isolated Perfused Segments of Rabbit Proximal Tubules

  Rudolfs K. Zalups, Lisa D. Parks, Vernon T. Cannon and Delon W. Barfuss

  Molecular Pharmacology August 1998, 54 (2) 353-363; DOI: https://doi.org/10.1124/mol.54.2.353
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  Role of the Extracellular Domains of the Cholecystokinin Receptor in Agonist Binding

  Sandrine Silvente-Poirot, Chantal Escrieut and Stephen A. Wank

  Molecular Pharmacology August 1998, 54 (2) 364-371; DOI: https://doi.org/10.1124/mol.54.2.364
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  ATP Receptor-Mediated Enhancement of Fast Excitatory Neurotransmitter Release in the Brain

  Baljit S. Khakh and Graeme Henderson

  Molecular Pharmacology August 1998, 54 (2) 372-378; DOI: https://doi.org/10.1124/mol.54.2.372
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  Identification of Transmembrane Regions Critical for Ligand Binding to the Human D₃ Dopamine Receptor Using Various D₃/D₁ Transmembrane Chimeras

  Glen L. Alberts, Jeffrey F. Pregenzer and Wha Bin Im

  Molecular Pharmacology August 1998, 54 (2) 379-388; DOI: https://doi.org/10.1124/mol.54.2.379
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  Local Anesthetic Block of Batrachotoxin-Resistant Muscle Na⁺ Channels

  Ging Kuo Wang, Catherine Quan and Sho-Ya Wang

  Molecular Pharmacology August 1998, 54 (2) 389-396; DOI: https://doi.org/10.1124/mol.54.2.389
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  Ethanol Potentiation of Calcium-Activated Potassium Channels Reconstituted into Planar Lipid Bilayers

  Benson Chu, Alejandro M. Dopico, José R. Lemos and Steven N. Treistman

  Molecular Pharmacology August 1998, 54 (2) 397-406; DOI: https://doi.org/10.1124/mol.54.2.397
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  Inhibition of Neuronal Calcium Channels by a Novel Peptide Spider Toxin, DW13.3

  Kathy G. Sutton, Chet Siok, Anthony Stea, Gerald W. Zamponi, Steven D. Heck, Robert A. Volkmann, Michael K. Ahlijanian and Terry P. Snutch

  Molecular Pharmacology August 1998, 54 (2) 407-418; DOI: https://doi.org/10.1124/mol.54.2.407
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  Regulation of Adenylyl Cyclase Isozymes on Acute and Chronic Activation of Inhibitory Receptors

  Igal Nevo, Tomer Avidor-Reiss, Rivka Levy, Michael Bayewitch, Eli Heldman and Zvi Vogel

  Molecular Pharmacology August 1998, 54 (2) 419-426; DOI: https://doi.org/10.1124/mol.54.2.419
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  Dependence of AT₁ Angiotensin Receptor Function on Adjacent Asparagine Residues in the Seventh Transmembrane Helix

  László Hunyady, Hong Ji, Gowraganahalli Jagadeesh, Meng Zhang, Zsuzsanna Gáborik, Balázs Mihalik and Kevin J. Catt

  Molecular Pharmacology August 1998, 54 (2) 427-434; DOI: https://doi.org/10.1124/mol.54.2.427
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  Contribution of Serine Residues to Constitutive and Agonist-Induced Signaling via the D_2SDopamine Receptor: Evidence for Multiple, Agonist-Specific Active Conformations

  Brenda L. Wiens, Cole S. Nelson and Kim A. Neve

  Molecular Pharmacology August 1998, 54 (2) 435-444; DOI: https://doi.org/10.1124/mol.54.2.435
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  Nonredox 5-Lipoxygenase Inhibitors Require Glutathione Peroxidase for Efficient Inhibition of 5-Lipoxygenase Activity

  Oliver Werz, Dagmar Szellas, Margarete Henseler and Dieter Steinhilber

  Molecular Pharmacology August 1998, 54 (2) 445-451; DOI: https://doi.org/10.1124/mol.54.2.445