Abstract
I suggested in the accompanying article [Mol Pharmacol2001;59:875–885] that muscarinic receptors catalyzed G protein activation. Acetylcholine or carbamylcholine recognition facilitated not only the GDP release from receptor-coupled inactive G proteins but also the release ofG
Footnotes
- Received August 8, 2000.
- Accepted January 9, 2001.
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Send reprint requests to: Dr. Waelbroeck, Laboratoire de Chimie Biologique et de la Nutrition, Faculté de Médecine de l'Université Libre de Bruxelles, Bât. G/E, CP 611, 808 Route de Lennik, B–1070 Brussels, Belgium. E-mail: mawaelbr{at}ulb.ac.be
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Supported by Grant 3.4504.99 from the Fonds de la Recherche Scientifique Médicale, by an “Action de Recherche Concertée” from the “Communauté Française de Belgique” and by a “Interuniversity Poles of Attraction Program - Belgian State, Prime Minister's Office - Federal Office for Scientific, Technical and Cultural Affairs”.
- The American Society for Pharmacology and Experimental Therapeutics
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