Correction to “Preferential formation of MT1/MT2 melatonin receptor heterodimers with distinct ligand interaction properties compared with MT2 homodimers”
In the above article [Ayoub MA, Levoye A, Delagrange P, and Jockers R (2004) Mol Pharmacol66:312–321], information regarding the ligands in Fig. 5 was removed in error during copyediting. A corrected version of Fig. 5 appears below. The online version has been corrected in departure from the print version.
Correlations between EC50 values of MT1/MT2 heterodimers and Ki values of MT1 and MT2 receptors. EC50 values of the MT1/MT2 heterodimer shown in Table 4 were plotted against Ki values determined in cells coexpressing MT1 and MT2 receptors (A) or expressing MT1-Rluc (B) or MT2-YFP (C) receptors individually. D, correlation between EC50 values of the MT2 homodimer and the MT1/MT2 heterodimer. Ligands: 1, melatonin; 2, S20098; 3, S22153; 4, S20928; 5, 4P-PDOT; 6, luzindole; 7, S24773; 8, 2-iodomelatonin. B and C, nonselective (•) and selective (○) compounds. Ligand 9 shown in B corresponds to the MT1-selective S26284 compound. Data were fitted using a linear regression equation (GraphPad Prism software).
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