Abstract
Cell-penetrating peptides are amphipathic or cationic oligopeptides able to transport covalently attached cargoes across cell membranes. Peptide aptamers are polypeptide fragments of endogenous proteins that mimic and thus perturb interactions with other cellular proteins. Combining aptamer and CPP technology can generate pharmacological reagents effective in cell culture models and in vivo.
- Received January 25, 2005.
- Accepted January 25, 2005.
- The American Society for Pharmacology and Experimental Therapeutics
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