Editor's Note Regarding “Mechanism of Corticotropin-Releasing Factor Type I Receptor Regulation by Nonpeptide Antagonists”

In the above article [Hoare SR, Sullivan SK, Ling N, Crowe PD, and Grigoriadis DE (2003) Mol Pharmacol63:751–765], the authors used a compound, NBI 35965, for which the chemical name and structure were not provided at the time of the original publication. The authors have now made this structure available (below) for interested readers.

View larger version:

• In this window
• In a new window

NBI 35965 [(S)-6-cyclopropylmethyl-2-(2,4-dichlorophenyl)-7-ethyl-4-methyl-7,8-dihydro-6H-1,3,6,8a-tetraaza-acenaphthylene mesylate].