Abstract
This Perspective focuses on the α1D-adrenergic receptor (AR), the often neglected sibling of the α1-AR family. This neglect is due in part to its poor cell-surface expression. However, it has recently been shown that dimerization of the α1D-AR with either the α1B-AR or the β2-AR increases α1D-AR cell-surface expression, and in this issue of Molecular Pharmacology, Hague et al. (p. 45) demonstrate that dimerization of the α1D-AR with the α1B-AR not only leads to increased cell-surface expression but also results in the formation of a novel functional entity.
- The American Society for Pharmacology and Experimental Therapeutics
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In this issue
The α1D-Adrenergic Receptor: Cinderella or Ugly Stepsister
