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OtherPerspective

The α1D-Adrenergic Receptor: Cinderella or Ugly Stepsister

Angela M. Finch and Robert M. Graham
Molecular Pharmacology January 2006, 69 (1) 1-4; DOI: https://doi.org/10.1124/mol.105.020230
Angela M. Finch
Molecular Cardiology Program, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia
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Robert M. Graham
Molecular Cardiology Program, Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia
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Abstract

This Perspective focuses on the α1D-adrenergic receptor (AR), the often neglected sibling of the α1-AR family. This neglect is due in part to its poor cell-surface expression. However, it has recently been shown that dimerization of the α1D-AR with either the α1B-AR or the β2-AR increases α1D-AR cell-surface expression, and in this issue of Molecular Pharmacology, Hague et al. (p. 45) demonstrate that dimerization of the α1D-AR with the α1B-AR not only leads to increased cell-surface expression but also results in the formation of a novel functional entity.

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Molecular Pharmacology: 69 (1)
Molecular Pharmacology
Vol. 69, Issue 1
1 Jan 2006
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OtherPerspective

The α1D-Adrenergic Receptor: Cinderella or Ugly Stepsister

Angela M. Finch and Robert M. Graham
Molecular Pharmacology January 1, 2006, 69 (1) 1-4; DOI: https://doi.org/10.1124/mol.105.020230

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OtherPerspective

The α1D-Adrenergic Receptor: Cinderella or Ugly Stepsister

Angela M. Finch and Robert M. Graham
Molecular Pharmacology January 1, 2006, 69 (1) 1-4; DOI: https://doi.org/10.1124/mol.105.020230
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