Research ArticleArticle
RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB
Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara II
Molecular Pharmacology October 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220
Yang Zhong Huang
Department of Neurobiology (Y.Z.H.) and Department of Pharmacology and Cancer Biology (B.G.), Duke University Medical Center, Duke University, Durham, North Carolina; Department of Internal Medicine (F.J.H., K.R.S., P.H.G., J.O.M.), Center for Bioinformatics and Computational Biology (K.N., T.E.S.), Department of Biomedical Engineering (K.N., T.E.S.), and Department of Ophthalmology and Visual Sciences (T.E.S.), Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa; Integrated DNA Technologies, Coralville, Iowa (M.A.B., A.S.P.); and DNA Facility, University of Iowa, Iowa City, Iowa (T.B.)
Frank J. Hernandez
Department of Neurobiology (Y.Z.H.) and Department of Pharmacology and Cancer Biology (B.G.), Duke University Medical Center, Duke University, Durham, North Carolina; Department of Internal Medicine (F.J.H., K.R.S., P.H.G., J.O.M.), Center for Bioinformatics and Computational Biology (K.N., T.E.S.), Department of Biomedical Engineering (K.N., T.E.S.), and Department of Ophthalmology and Visual Sciences (T.E.S.), Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa; Integrated DNA Technologies, Coralville, Iowa (M.A.B., A.S.P.); and DNA Facility, University of Iowa, Iowa City, Iowa (T.B.)
Bin Gu
Department of Neurobiology (Y.Z.H.) and Department of Pharmacology and Cancer Biology (B.G.), Duke University Medical Center, Duke University, Durham, North Carolina; Department of Internal Medicine (F.J.H., K.R.S., P.H.G., J.O.M.), Center for Bioinformatics and Computational Biology (K.N., T.E.S.), Department of Biomedical Engineering (K.N., T.E.S.), and Department of Ophthalmology and Visual Sciences (T.E.S.), Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa; Integrated DNA Technologies, Coralville, Iowa (M.A.B., A.S.P.); and DNA Facility, University of Iowa, Iowa City, Iowa (T.B.)
Katie R. Stockdale
Department of Neurobiology (Y.Z.H.) and Department of Pharmacology and Cancer Biology (B.G.), Duke University Medical Center, Duke University, Durham, North Carolina; Department of Internal Medicine (F.J.H., K.R.S., P.H.G., J.O.M.), Center for Bioinformatics and Computational Biology (K.N., T.E.S.), Department of Biomedical Engineering (K.N., T.E.S.), and Department of Ophthalmology and Visual Sciences (T.E.S.), Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa; Integrated DNA Technologies, Coralville, Iowa (M.A.B., A.S.P.); and DNA Facility, University of Iowa, Iowa City, Iowa (T.B.)
Kishore Nanapaneni
Department of Neurobiology (Y.Z.H.) and Department of Pharmacology and Cancer Biology (B.G.), Duke University Medical Center, Duke University, Durham, North Carolina; Department of Internal Medicine (F.J.H., K.R.S., P.H.G., J.O.M.), Center for Bioinformatics and Computational Biology (K.N., T.E.S.), Department of Biomedical Engineering (K.N., T.E.S.), and Department of Ophthalmology and Visual Sciences (T.E.S.), Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa; Integrated DNA Technologies, Coralville, Iowa (M.A.B., A.S.P.); and DNA Facility, University of Iowa, Iowa City, Iowa (T.B.)
Todd E. Scheetz
Department of Neurobiology (Y.Z.H.) and Department of Pharmacology and Cancer Biology (B.G.), Duke University Medical Center, Duke University, Durham, North Carolina; Department of Internal Medicine (F.J.H., K.R.S., P.H.G., J.O.M.), Center for Bioinformatics and Computational Biology (K.N., T.E.S.), Department of Biomedical Engineering (K.N., T.E.S.), and Department of Ophthalmology and Visual Sciences (T.E.S.), Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa; Integrated DNA Technologies, Coralville, Iowa (M.A.B., A.S.P.); and DNA Facility, University of Iowa, Iowa City, Iowa (T.B.)
Mark A. Behlke
Department of Neurobiology (Y.Z.H.) and Department of Pharmacology and Cancer Biology (B.G.), Duke University Medical Center, Duke University, Durham, North Carolina; Department of Internal Medicine (F.J.H., K.R.S., P.H.G., J.O.M.), Center for Bioinformatics and Computational Biology (K.N., T.E.S.), Department of Biomedical Engineering (K.N., T.E.S.), and Department of Ophthalmology and Visual Sciences (T.E.S.), Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa; Integrated DNA Technologies, Coralville, Iowa (M.A.B., A.S.P.); and DNA Facility, University of Iowa, Iowa City, Iowa (T.B.)
Andrew S. Peek
Department of Neurobiology (Y.Z.H.) and Department of Pharmacology and Cancer Biology (B.G.), Duke University Medical Center, Duke University, Durham, North Carolina; Department of Internal Medicine (F.J.H., K.R.S., P.H.G., J.O.M.), Center for Bioinformatics and Computational Biology (K.N., T.E.S.), Department of Biomedical Engineering (K.N., T.E.S.), and Department of Ophthalmology and Visual Sciences (T.E.S.), Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa; Integrated DNA Technologies, Coralville, Iowa (M.A.B., A.S.P.); and DNA Facility, University of Iowa, Iowa City, Iowa (T.B.)
Thomas Bair
Department of Neurobiology (Y.Z.H.) and Department of Pharmacology and Cancer Biology (B.G.), Duke University Medical Center, Duke University, Durham, North Carolina; Department of Internal Medicine (F.J.H., K.R.S., P.H.G., J.O.M.), Center for Bioinformatics and Computational Biology (K.N., T.E.S.), Department of Biomedical Engineering (K.N., T.E.S.), and Department of Ophthalmology and Visual Sciences (T.E.S.), Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa; Integrated DNA Technologies, Coralville, Iowa (M.A.B., A.S.P.); and DNA Facility, University of Iowa, Iowa City, Iowa (T.B.)
Paloma H. Giangrande
Department of Neurobiology (Y.Z.H.) and Department of Pharmacology and Cancer Biology (B.G.), Duke University Medical Center, Duke University, Durham, North Carolina; Department of Internal Medicine (F.J.H., K.R.S., P.H.G., J.O.M.), Center for Bioinformatics and Computational Biology (K.N., T.E.S.), Department of Biomedical Engineering (K.N., T.E.S.), and Department of Ophthalmology and Visual Sciences (T.E.S.), Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa; Integrated DNA Technologies, Coralville, Iowa (M.A.B., A.S.P.); and DNA Facility, University of Iowa, Iowa City, Iowa (T.B.)
James O. McNamara II
Department of Neurobiology (Y.Z.H.) and Department of Pharmacology and Cancer Biology (B.G.), Duke University Medical Center, Duke University, Durham, North Carolina; Department of Internal Medicine (F.J.H., K.R.S., P.H.G., J.O.M.), Center for Bioinformatics and Computational Biology (K.N., T.E.S.), Department of Biomedical Engineering (K.N., T.E.S.), and Department of Ophthalmology and Visual Sciences (T.E.S.), Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa; Integrated DNA Technologies, Coralville, Iowa (M.A.B., A.S.P.); and DNA Facility, University of Iowa, Iowa City, Iowa (T.B.)
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Research ArticleArticle
Functional RNA Ligands for TrkB
Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara
Molecular Pharmacology October 1, 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220
Research ArticleArticle
Functional RNA Ligands for TrkB
Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara
Molecular Pharmacology October 1, 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220
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