Research ArticleArticle
Neurounina-1, a Novel Compound That Increases Na+/Ca2+ Exchanger Activity, Effectively Protects against Stroke Damage
Pasquale Molinaro, Maria Cantile, Ornella Cuomo, Agnese Secondo, Anna Pannaccione, Paolo Ambrosino, Giuseppe Pignataro, Ferdinando Fiorino, Beatrice Severino, Elena Gatta, Maria José Sisalli, Marco Milanese, Antonella Scorziello, Giambattista Bonanno, Mauro Robello, Vincenzo Santagada, Giuseppe Caliendo, Gianfranco Di Renzo and Lucio Annunziato
Molecular Pharmacology January 2013, 83 (1) 142-156; DOI: https://doi.org/10.1124/mol.112.080986
Pasquale Molinaro
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Maria Cantile
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Ornella Cuomo
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Agnese Secondo
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Anna Pannaccione
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Paolo Ambrosino
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Giuseppe Pignataro
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Ferdinando Fiorino
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Beatrice Severino
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Elena Gatta
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Maria José Sisalli
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Marco Milanese
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Antonella Scorziello
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Giambattista Bonanno
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Mauro Robello
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Vincenzo Santagada
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Giuseppe Caliendo
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Gianfranco Di Renzo
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
Lucio Annunziato
Division of Pharmacology, Department of Neuroscience, School of Medicine, “Federico II” University of Naples-National Institute of Neuroscience, Naples, Italy (P.M., M.C., O.C., A.Se., A.P., P.A., G.P., M.J.S., A.Sc., G.D.R., L.A.); Department of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, “Federico II” University of Naples, Naples, Italy (F.F., B.S., V.S., G.C.); and Department of Physics (E.G., M.R.) and Department of Experimental Medicine, Section of Pharmacology and Toxicology, University of Genoa, Genoa, Italy (M.M., G.B.)
MolPharm articles become freely available 12 months after publication, and remain freely available for 5 years.Non-open access articles that fall outside this five year window are available only to institutional subscribers and current ASPET members, or through the article purchase feature at the bottom of the page.
|
Log in using your username and password
Purchase access
You may purchase access to this article. This will require you to create an account if you don't already have one.
In this issue
Research ArticleArticle
Neurounina-1 Increases NCX Activity and Protects against Stroke
Pasquale Molinaro, Maria Cantile, Ornella Cuomo, Agnese Secondo, Anna Pannaccione, Paolo Ambrosino, Giuseppe Pignataro, Ferdinando Fiorino, Beatrice Severino, Elena Gatta, Maria José Sisalli, Marco Milanese, Antonella Scorziello, Giambattista Bonanno, Mauro Robello, Vincenzo Santagada, Giuseppe Caliendo, Gianfranco Di Renzo and Lucio Annunziato
Molecular Pharmacology January 1, 2013, 83 (1) 142-156; DOI: https://doi.org/10.1124/mol.112.080986
Research ArticleArticle
Neurounina-1 Increases NCX Activity and Protects against Stroke
Pasquale Molinaro, Maria Cantile, Ornella Cuomo, Agnese Secondo, Anna Pannaccione, Paolo Ambrosino, Giuseppe Pignataro, Ferdinando Fiorino, Beatrice Severino, Elena Gatta, Maria José Sisalli, Marco Milanese, Antonella Scorziello, Giambattista Bonanno, Mauro Robello, Vincenzo Santagada, Giuseppe Caliendo, Gianfranco Di Renzo and Lucio Annunziato
Molecular Pharmacology January 1, 2013, 83 (1) 142-156; DOI: https://doi.org/10.1124/mol.112.080986
Jump to section
Related Articles
Cited By...
More in this TOC Section
Similar Articles
Advertisement