Research ArticleArticle
Identification of Determinants Required for Agonistic and Inverse Agonistic Ligand Properties at the ADP Receptor P2Y12
Philipp Schmidt, Lars Ritscher, Elizabeth N. Dong, Thomas Hermsdorf, Maxi Cöster, Doreen Wittkopf, Jens Meiler and Torsten Schöneberg
Molecular Pharmacology January 2013, 83 (1) 256-266; DOI: https://doi.org/10.1124/mol.112.082198
Philipp Schmidt
Molecular Biochemistry, Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany (P.S., L.R., T.H., M.C., D.W., T.S.); and Center for Structural Biology, (E.N.D., J.M.), Department of Pharmacology, Vanderbilt Program in Drug Discovery, and Department of Chemistry and the Institute for Chemical Biology, Vanderbilt University Medical Center, Nashville, Tennessee (J.M.)
Lars Ritscher
Molecular Biochemistry, Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany (P.S., L.R., T.H., M.C., D.W., T.S.); and Center for Structural Biology, (E.N.D., J.M.), Department of Pharmacology, Vanderbilt Program in Drug Discovery, and Department of Chemistry and the Institute for Chemical Biology, Vanderbilt University Medical Center, Nashville, Tennessee (J.M.)
Elizabeth N. Dong
Molecular Biochemistry, Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany (P.S., L.R., T.H., M.C., D.W., T.S.); and Center for Structural Biology, (E.N.D., J.M.), Department of Pharmacology, Vanderbilt Program in Drug Discovery, and Department of Chemistry and the Institute for Chemical Biology, Vanderbilt University Medical Center, Nashville, Tennessee (J.M.)
Thomas Hermsdorf
Molecular Biochemistry, Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany (P.S., L.R., T.H., M.C., D.W., T.S.); and Center for Structural Biology, (E.N.D., J.M.), Department of Pharmacology, Vanderbilt Program in Drug Discovery, and Department of Chemistry and the Institute for Chemical Biology, Vanderbilt University Medical Center, Nashville, Tennessee (J.M.)
Maxi Cöster
Molecular Biochemistry, Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany (P.S., L.R., T.H., M.C., D.W., T.S.); and Center for Structural Biology, (E.N.D., J.M.), Department of Pharmacology, Vanderbilt Program in Drug Discovery, and Department of Chemistry and the Institute for Chemical Biology, Vanderbilt University Medical Center, Nashville, Tennessee (J.M.)
Doreen Wittkopf
Molecular Biochemistry, Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany (P.S., L.R., T.H., M.C., D.W., T.S.); and Center for Structural Biology, (E.N.D., J.M.), Department of Pharmacology, Vanderbilt Program in Drug Discovery, and Department of Chemistry and the Institute for Chemical Biology, Vanderbilt University Medical Center, Nashville, Tennessee (J.M.)
Jens Meiler
Molecular Biochemistry, Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany (P.S., L.R., T.H., M.C., D.W., T.S.); and Center for Structural Biology, (E.N.D., J.M.), Department of Pharmacology, Vanderbilt Program in Drug Discovery, and Department of Chemistry and the Institute for Chemical Biology, Vanderbilt University Medical Center, Nashville, Tennessee (J.M.)
Torsten Schöneberg
Molecular Biochemistry, Institute of Biochemistry, Medical Faculty, University of Leipzig, Leipzig, Germany (P.S., L.R., T.H., M.C., D.W., T.S.); and Center for Structural Biology, (E.N.D., J.M.), Department of Pharmacology, Vanderbilt Program in Drug Discovery, and Department of Chemistry and the Institute for Chemical Biology, Vanderbilt University Medical Center, Nashville, Tennessee (J.M.)
Submit a Response to This Article
Jump to comment:
No eLetters have been published for this article.
In this issue
Research ArticleArticle
Inverse Agonists at P2Y12
Philipp Schmidt, Lars Ritscher, Elizabeth N. Dong, Thomas Hermsdorf, Maxi Cöster, Doreen Wittkopf, Jens Meiler and Torsten Schöneberg
Molecular Pharmacology January 1, 2013, 83 (1) 256-266; DOI: https://doi.org/10.1124/mol.112.082198
Jump to section
Related Articles
Cited By...
More in this TOC Section
Similar Articles
Advertisement