Research ArticleArticle
Salt Bridge Switching from Arg290/Glu167 to Arg290/ATP Promotes the Closed-to-Open Transition of the P2X2 Receptor
Ralf Hausmann, Janka Günther, Achim Kless, Daniel Kuhlmann, Matthias U. Kassack, Gregor Bahrenberg, Fritz Markwardt and Günther Schmalzing
Molecular Pharmacology January 2013, 83 (1) 73-84; DOI: https://doi.org/10.1124/mol.112.081489
Ralf Hausmann
Molecular Pharmacology, RWTH Aachen University, Aachen, Germany (R.H., J.G., D.K., G.S.); Grünenthal GmbH, Global Drug Discovery, Departments of Molecular Pharmacology and Discovery Informatics, Aachen, Germany (A.K., G.B.); Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany (M.U.K.); and Julius Bernstein Institute for Physiology, Martin Luther University, Halle/Saale, Germany (F.M.)
Janka Günther
Molecular Pharmacology, RWTH Aachen University, Aachen, Germany (R.H., J.G., D.K., G.S.); Grünenthal GmbH, Global Drug Discovery, Departments of Molecular Pharmacology and Discovery Informatics, Aachen, Germany (A.K., G.B.); Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany (M.U.K.); and Julius Bernstein Institute for Physiology, Martin Luther University, Halle/Saale, Germany (F.M.)
Achim Kless
Molecular Pharmacology, RWTH Aachen University, Aachen, Germany (R.H., J.G., D.K., G.S.); Grünenthal GmbH, Global Drug Discovery, Departments of Molecular Pharmacology and Discovery Informatics, Aachen, Germany (A.K., G.B.); Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany (M.U.K.); and Julius Bernstein Institute for Physiology, Martin Luther University, Halle/Saale, Germany (F.M.)
Daniel Kuhlmann
Molecular Pharmacology, RWTH Aachen University, Aachen, Germany (R.H., J.G., D.K., G.S.); Grünenthal GmbH, Global Drug Discovery, Departments of Molecular Pharmacology and Discovery Informatics, Aachen, Germany (A.K., G.B.); Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany (M.U.K.); and Julius Bernstein Institute for Physiology, Martin Luther University, Halle/Saale, Germany (F.M.)
Matthias U. Kassack
Molecular Pharmacology, RWTH Aachen University, Aachen, Germany (R.H., J.G., D.K., G.S.); Grünenthal GmbH, Global Drug Discovery, Departments of Molecular Pharmacology and Discovery Informatics, Aachen, Germany (A.K., G.B.); Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany (M.U.K.); and Julius Bernstein Institute for Physiology, Martin Luther University, Halle/Saale, Germany (F.M.)
Gregor Bahrenberg
Molecular Pharmacology, RWTH Aachen University, Aachen, Germany (R.H., J.G., D.K., G.S.); Grünenthal GmbH, Global Drug Discovery, Departments of Molecular Pharmacology and Discovery Informatics, Aachen, Germany (A.K., G.B.); Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany (M.U.K.); and Julius Bernstein Institute for Physiology, Martin Luther University, Halle/Saale, Germany (F.M.)
Fritz Markwardt
Molecular Pharmacology, RWTH Aachen University, Aachen, Germany (R.H., J.G., D.K., G.S.); Grünenthal GmbH, Global Drug Discovery, Departments of Molecular Pharmacology and Discovery Informatics, Aachen, Germany (A.K., G.B.); Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany (M.U.K.); and Julius Bernstein Institute for Physiology, Martin Luther University, Halle/Saale, Germany (F.M.)
Günther Schmalzing
Molecular Pharmacology, RWTH Aachen University, Aachen, Germany (R.H., J.G., D.K., G.S.); Grünenthal GmbH, Global Drug Discovery, Departments of Molecular Pharmacology and Discovery Informatics, Aachen, Germany (A.K., G.B.); Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany (M.U.K.); and Julius Bernstein Institute for Physiology, Martin Luther University, Halle/Saale, Germany (F.M.)
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Research ArticleArticle
Salt Bridge Switching in P2X2 Receptor Gating
Ralf Hausmann, Janka Günther, Achim Kless, Daniel Kuhlmann, Matthias U. Kassack, Gregor Bahrenberg, Fritz Markwardt and Günther Schmalzing
Molecular Pharmacology January 1, 2013, 83 (1) 73-84; DOI: https://doi.org/10.1124/mol.112.081489
Research ArticleArticle
Salt Bridge Switching in P2X2 Receptor Gating
Ralf Hausmann, Janka Günther, Achim Kless, Daniel Kuhlmann, Matthias U. Kassack, Gregor Bahrenberg, Fritz Markwardt and Günther Schmalzing
Molecular Pharmacology January 1, 2013, 83 (1) 73-84; DOI: https://doi.org/10.1124/mol.112.081489
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