Research ArticleArticle
Ticlopidine, a Cholestatic Liver Injury-Inducible Drug, Causes Dysfunction of Bile Formation via Diminished Biliary Secretion of Phospholipids: Involvement of Biliary-Excreted Glutathione-Conjugated Ticlopidine Metabolites
Takashi Yoshikado, Tappei Takada, Hideaki Yamamoto, Jeng Kae Tan, Kousei Ito, Tomofumi Santa and Hiroshi Suzuki
Molecular Pharmacology February 2013, 83 (2) 552-562; DOI: https://doi.org/10.1124/mol.112.081752
Takashi Yoshikado
Department of Pharmacy, the University of Tokyo Hospital, Faculty of Medicine, (T.Y., T.T., H.Y., J.K.T., K.I., H.S.), Laboratory of Biomedical and Pharmaceutical Analysis, Graduate School of Pharmaceutical Sciences, the University of Tokyo, Tokyo, Japan (T.Y., T.S.)
Tappei Takada
Department of Pharmacy, the University of Tokyo Hospital, Faculty of Medicine, (T.Y., T.T., H.Y., J.K.T., K.I., H.S.), Laboratory of Biomedical and Pharmaceutical Analysis, Graduate School of Pharmaceutical Sciences, the University of Tokyo, Tokyo, Japan (T.Y., T.S.)
Hideaki Yamamoto
Department of Pharmacy, the University of Tokyo Hospital, Faculty of Medicine, (T.Y., T.T., H.Y., J.K.T., K.I., H.S.), Laboratory of Biomedical and Pharmaceutical Analysis, Graduate School of Pharmaceutical Sciences, the University of Tokyo, Tokyo, Japan (T.Y., T.S.)
Jeng Kae Tan
Department of Pharmacy, the University of Tokyo Hospital, Faculty of Medicine, (T.Y., T.T., H.Y., J.K.T., K.I., H.S.), Laboratory of Biomedical and Pharmaceutical Analysis, Graduate School of Pharmaceutical Sciences, the University of Tokyo, Tokyo, Japan (T.Y., T.S.)
Kousei Ito
Department of Pharmacy, the University of Tokyo Hospital, Faculty of Medicine, (T.Y., T.T., H.Y., J.K.T., K.I., H.S.), Laboratory of Biomedical and Pharmaceutical Analysis, Graduate School of Pharmaceutical Sciences, the University of Tokyo, Tokyo, Japan (T.Y., T.S.)
Tomofumi Santa
Department of Pharmacy, the University of Tokyo Hospital, Faculty of Medicine, (T.Y., T.T., H.Y., J.K.T., K.I., H.S.), Laboratory of Biomedical and Pharmaceutical Analysis, Graduate School of Pharmaceutical Sciences, the University of Tokyo, Tokyo, Japan (T.Y., T.S.)
Hiroshi Suzuki
Department of Pharmacy, the University of Tokyo Hospital, Faculty of Medicine, (T.Y., T.T., H.Y., J.K.T., K.I., H.S.), Laboratory of Biomedical and Pharmaceutical Analysis, Graduate School of Pharmaceutical Sciences, the University of Tokyo, Tokyo, Japan (T.Y., T.S.)
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Effect of Ticlopidine on Bile Formation
Takashi Yoshikado, Tappei Takada, Hideaki Yamamoto, Jeng Kae Tan, Kousei Ito, Tomofumi Santa and Hiroshi Suzuki
Molecular Pharmacology February 1, 2013, 83 (2) 552-562; DOI: https://doi.org/10.1124/mol.112.081752
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