Research ArticleArticle
Phage Display–Mediated Discovery of Novel Tyrosinase-Targeting Tetrapeptide Inhibitors Reveals the Significance of N-Terminal Preference of Cysteine Residues and Their Functional Sulfur Atom
Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
Molecular Pharmacology February 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185
Yu-Ching Lee
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Nai-Wan Hsiao
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Tien-Sheng Tseng
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Wang-Chuan Chen
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Hui-Hsiung Lin
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Sy-Jye Leu
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Ei-Wen Yang
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
Keng-Chang Tsai
The Center of Translational Medicine, Antibody and Hybridoma Core Facility (Y.-C.L.), and Graduate Institute of Medical Sciences, Department of Microbiology and Immunology, School of Medicine, College of Medicine (S.-J.L.), Taipei Medical University, Taipei, Taiwan; Institute of Biotechnology, National Changhua University of Education, Changhua, Taiwan (N.-W.H., T.-S.T., H.-H.L.); National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan (T.-S.T., H.-H.L., K.-C.T.); The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan (W.-C.C.); Department of Chinese Medicine, E-Da hospital, Kaohsiung, Taiwan (W.-C.C.); and Department of Computer Science and Engineering, University of California, Riverside, California (E.-W.Y.)
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Research ArticleArticle
Tyrosinase Inhibitor Discovery and Molecular Docking
Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
Molecular Pharmacology February 1, 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185
Research ArticleArticle
Tyrosinase Inhibitor Discovery and Molecular Docking
Yu-Ching Lee, Nai-Wan Hsiao, Tien-Sheng Tseng, Wang-Chuan Chen, Hui-Hsiung Lin, Sy-Jye Leu, Ei-Wen Yang and Keng-Chang Tsai
Molecular Pharmacology February 1, 2015, 87 (2) 218-230; DOI: https://doi.org/10.1124/mol.114.094185
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