Research ArticleArticle
Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function
Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
Molecular Pharmacology February 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737
Arnault Massink
Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands (A.M., E.B.L., N.V.O.Z., L.X., L.H.H., A.P.IJ.); Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden (H.G.T.); and Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California (V.K., R.C.S.)
Hugo Gutiérrez-de-Terán
Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands (A.M., E.B.L., N.V.O.Z., L.X., L.H.H., A.P.IJ.); Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden (H.G.T.); and Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California (V.K., R.C.S.)
Eelke B. Lenselink
Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands (A.M., E.B.L., N.V.O.Z., L.X., L.H.H., A.P.IJ.); Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden (H.G.T.); and Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California (V.K., R.C.S.)
Natalia V. Ortiz Zacarías
Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands (A.M., E.B.L., N.V.O.Z., L.X., L.H.H., A.P.IJ.); Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden (H.G.T.); and Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California (V.K., R.C.S.)
Lizi Xia
Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands (A.M., E.B.L., N.V.O.Z., L.X., L.H.H., A.P.IJ.); Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden (H.G.T.); and Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California (V.K., R.C.S.)
Laura H. Heitman
Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands (A.M., E.B.L., N.V.O.Z., L.X., L.H.H., A.P.IJ.); Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden (H.G.T.); and Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California (V.K., R.C.S.)
Vsevolod Katritch
Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands (A.M., E.B.L., N.V.O.Z., L.X., L.H.H., A.P.IJ.); Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden (H.G.T.); and Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California (V.K., R.C.S.)
Raymond C. Stevens
Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands (A.M., E.B.L., N.V.O.Z., L.X., L.H.H., A.P.IJ.); Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden (H.G.T.); and Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California (V.K., R.C.S.)
Adriaan P. IJzerman
Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands (A.M., E.B.L., N.V.O.Z., L.X., L.H.H., A.P.IJ.); Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden (H.G.T.); and Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California (V.K., R.C.S.)
Submit a Response to This Article
Jump to comment:
No eLetters have been published for this article.
In this issue
Research ArticleArticle
Na+ Pocket Mutations and Adenosine A2A Receptor Function
Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
Molecular Pharmacology February 1, 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737
Research ArticleArticle
Na+ Pocket Mutations and Adenosine A2A Receptor Function
Arnault Massink, Hugo Gutiérrez-de-Terán, Eelke B. Lenselink, Natalia V. Ortiz Zacarías, Lizi Xia, Laura H. Heitman, Vsevolod Katritch, Raymond C. Stevens and Adriaan P. IJzerman
Molecular Pharmacology February 1, 2015, 87 (2) 305-313; DOI: https://doi.org/10.1124/mol.114.095737
Jump to section
Related Articles
Cited By...
More in this TOC Section
Similar Articles
Advertisement