Rapid CommunicationMinireview—Exploring the biology of GPCRs: from in vitro to in vivo
Fulfilling the Promise of "Biased" G Protein–Coupled Receptor Agonism
Louis M. Luttrell, Stuart Maudsley and Laura M. Bohn
Molecular Pharmacology September 2015, 88 (3) 579-588; DOI: https://doi.org/10.1124/mol.115.099630
Louis M. Luttrell
Departments of Medicine and Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina (L.M.L.); Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina (L.M.L.); Translational Neurobiology Group, VIB Department of Molecular Genetics, Laboratory of Neurogenetics-Institute Born-Bunge, University of Antwerp, Belgium (S.M.); and Department of Molecular Therapeutics and Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida (L.M.B.)
Stuart Maudsley
Departments of Medicine and Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina (L.M.L.); Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina (L.M.L.); Translational Neurobiology Group, VIB Department of Molecular Genetics, Laboratory of Neurogenetics-Institute Born-Bunge, University of Antwerp, Belgium (S.M.); and Department of Molecular Therapeutics and Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida (L.M.B.)
Laura M. Bohn
Departments of Medicine and Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina (L.M.L.); Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina (L.M.L.); Translational Neurobiology Group, VIB Department of Molecular Genetics, Laboratory of Neurogenetics-Institute Born-Bunge, University of Antwerp, Belgium (S.M.); and Department of Molecular Therapeutics and Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida (L.M.B.)
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Rapid CommunicationMinireview—Exploring the biology of GPCRs: from in vitro to in vivo
Climate Change in GPCR Drug Discovery?
Louis M. Luttrell, Stuart Maudsley and Laura M. Bohn
Molecular Pharmacology September 1, 2015, 88 (3) 579-588; DOI: https://doi.org/10.1124/mol.115.099630
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