Research ArticleArticle
WNT Stimulation Dissociates a Frizzled 4 Inactive-State Complex with Gα12/13
Elisa Arthofer, Belma Hot, Julian Petersen, Katerina Strakova, Stefan Jäger, Manuel Grundmann, Evi Kostenis, J. Silvio Gutkind and Gunnar Schulte
Molecular Pharmacology October 2016, 90 (4) 447-459; DOI: https://doi.org/10.1124/mol.116.104919
Elisa Arthofer
Section of Receptor Biology and Signaling, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (E.A., B.H., J.P., K.S., S.J., G.S.); Section on Molecular Signal Transduction, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland (E.A.); Faculty of Science, Institute of Experimental Biology, Masaryk University, Brno, Czech Republic (K.S., G.S.); Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany (M.G., E.K.); Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, California (J.S.G.)
Belma Hot
Section of Receptor Biology and Signaling, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (E.A., B.H., J.P., K.S., S.J., G.S.); Section on Molecular Signal Transduction, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland (E.A.); Faculty of Science, Institute of Experimental Biology, Masaryk University, Brno, Czech Republic (K.S., G.S.); Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany (M.G., E.K.); Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, California (J.S.G.)
Julian Petersen
Section of Receptor Biology and Signaling, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (E.A., B.H., J.P., K.S., S.J., G.S.); Section on Molecular Signal Transduction, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland (E.A.); Faculty of Science, Institute of Experimental Biology, Masaryk University, Brno, Czech Republic (K.S., G.S.); Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany (M.G., E.K.); Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, California (J.S.G.)
Katerina Strakova
Section of Receptor Biology and Signaling, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (E.A., B.H., J.P., K.S., S.J., G.S.); Section on Molecular Signal Transduction, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland (E.A.); Faculty of Science, Institute of Experimental Biology, Masaryk University, Brno, Czech Republic (K.S., G.S.); Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany (M.G., E.K.); Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, California (J.S.G.)
Stefan Jäger
Section of Receptor Biology and Signaling, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (E.A., B.H., J.P., K.S., S.J., G.S.); Section on Molecular Signal Transduction, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland (E.A.); Faculty of Science, Institute of Experimental Biology, Masaryk University, Brno, Czech Republic (K.S., G.S.); Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany (M.G., E.K.); Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, California (J.S.G.)
Manuel Grundmann
Section of Receptor Biology and Signaling, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (E.A., B.H., J.P., K.S., S.J., G.S.); Section on Molecular Signal Transduction, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland (E.A.); Faculty of Science, Institute of Experimental Biology, Masaryk University, Brno, Czech Republic (K.S., G.S.); Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany (M.G., E.K.); Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, California (J.S.G.)
Evi Kostenis
Section of Receptor Biology and Signaling, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (E.A., B.H., J.P., K.S., S.J., G.S.); Section on Molecular Signal Transduction, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland (E.A.); Faculty of Science, Institute of Experimental Biology, Masaryk University, Brno, Czech Republic (K.S., G.S.); Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany (M.G., E.K.); Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, California (J.S.G.)
J. Silvio Gutkind
Section of Receptor Biology and Signaling, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (E.A., B.H., J.P., K.S., S.J., G.S.); Section on Molecular Signal Transduction, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland (E.A.); Faculty of Science, Institute of Experimental Biology, Masaryk University, Brno, Czech Republic (K.S., G.S.); Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany (M.G., E.K.); Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, California (J.S.G.)
Gunnar Schulte
Section of Receptor Biology and Signaling, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden (E.A., B.H., J.P., K.S., S.J., G.S.); Section on Molecular Signal Transduction, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland (E.A.); Faculty of Science, Institute of Experimental Biology, Masaryk University, Brno, Czech Republic (K.S., G.S.); Molecular, Cellular and Pharmacobiology Section, Institute for Pharmaceutical Biology, University of Bonn, Bonn, Germany (M.G., E.K.); Department of Pharmacology, Moores Cancer Center, University of California, San Diego, La Jolla, California (J.S.G.)
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Research ArticleArticle
FZD4 Signaling via Gα12/13 to p115-RHOGEF
Elisa Arthofer, Belma Hot, Julian Petersen, Katerina Strakova, Stefan Jäger, Manuel Grundmann, Evi Kostenis, J. Silvio Gutkind and Gunnar Schulte
Molecular Pharmacology October 1, 2016, 90 (4) 447-459; DOI: https://doi.org/10.1124/mol.116.104919
Research ArticleArticle
FZD4 Signaling via Gα12/13 to p115-RHOGEF
Elisa Arthofer, Belma Hot, Julian Petersen, Katerina Strakova, Stefan Jäger, Manuel Grundmann, Evi Kostenis, J. Silvio Gutkind and Gunnar Schulte
Molecular Pharmacology October 1, 2016, 90 (4) 447-459; DOI: https://doi.org/10.1124/mol.116.104919
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