Research ArticleArticle
Open Access
Diversity of Nicotinic Acetylcholine Receptor Positive Allosteric Modulators Revealed by Mutagenesis and a Revised Structural Model
Joseph Newcombe, Anna Chatzidaki, Tom D. Sheppard, Maya Topf and Neil S. Millar
Molecular Pharmacology February 2018, 93 (2) 128-140; DOI: https://doi.org/10.1124/mol.117.110551
Joseph Newcombe
Departments of Chemistry (J.N., T.D.S.) and Neuroscience, Physiology and Pharmacology (A.C., N.S.M.), University College London, London, United Kingdom; and Institute of Structural and Molecular Biology, Birkbeck, University of London, London, United Kingdom (J.N., M.T.)
Anna Chatzidaki
Departments of Chemistry (J.N., T.D.S.) and Neuroscience, Physiology and Pharmacology (A.C., N.S.M.), University College London, London, United Kingdom; and Institute of Structural and Molecular Biology, Birkbeck, University of London, London, United Kingdom (J.N., M.T.)
Tom D. Sheppard
Departments of Chemistry (J.N., T.D.S.) and Neuroscience, Physiology and Pharmacology (A.C., N.S.M.), University College London, London, United Kingdom; and Institute of Structural and Molecular Biology, Birkbeck, University of London, London, United Kingdom (J.N., M.T.)
Maya Topf
Departments of Chemistry (J.N., T.D.S.) and Neuroscience, Physiology and Pharmacology (A.C., N.S.M.), University College London, London, United Kingdom; and Institute of Structural and Molecular Biology, Birkbeck, University of London, London, United Kingdom (J.N., M.T.)
Neil S. Millar
Departments of Chemistry (J.N., T.D.S.) and Neuroscience, Physiology and Pharmacology (A.C., N.S.M.), University College London, London, United Kingdom; and Institute of Structural and Molecular Biology, Birkbeck, University of London, London, United Kingdom (J.N., M.T.)
Submit a Response to This Article
Jump to comment:
No eLetters have been published for this article.
In this issue
Research ArticleArticle
Structural Model and Allosteric Modulators of the α7 nAChR
Joseph Newcombe, Anna Chatzidaki, Tom D. Sheppard, Maya Topf and Neil S. Millar
Molecular Pharmacology February 1, 2018, 93 (2) 128-140; DOI: https://doi.org/10.1124/mol.117.110551
Jump to section
Related Articles
Cited By...
More in this TOC Section
Similar Articles
Advertisement