Article Figures & Data
Figures
Additional Files
Data Supplement
- Supplemental Data -
Supplementary Figure 1 - Relationship between RyR1 channel activity and [Ca2+]ER in HEK293 cells expressing wild-type (WT, filled circle) or mutations associated with MH (open circles) and MH/CCD (crosses) in the central region
Supplementary Figure 2 - Effect of caffeine on [Ca2+]ER in the WT RyR1 cells. (A) In the WT RyR1 cells, caffeine activates the RyR1 channels to cause Ca2+ leakage from ER
Supplementary Table 1 - Compounds that increased F/F0 in WT cells by >3 SDs
Supplementary Table 2 - Effects of hit and related compounds on [Ca2+]ER of mutant and WT RyR1 cells
- Supplemental Data -