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Allergen Delivery Inhibitors: A Rationale for Targeting Sentinel Innate Immune Signaling of Group 1 House Dust Mite Allergens through Structure-Based Protease Inhibitor Design
Jihui Zhang, Jie Chen, Gary K. Newton, Trevor R. Perrior and Clive Robinson
Molecular Pharmacology September 2018, 94 (3) 1007-1030; DOI: https://doi.org/10.1124/mol.118.112730
Jihui Zhang
Institute for Infection and Immunity, St George’s, University of London, London, United Kingdom (J.Z., J.C., C.R.); State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People’s Republic of China (J.Z.); and Domainex Ltd., Chesterford Research Park, Saffron Walden, United Kingdom (G.K.N., T.R.P.)
Jie Chen
Institute for Infection and Immunity, St George’s, University of London, London, United Kingdom (J.Z., J.C., C.R.); State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People’s Republic of China (J.Z.); and Domainex Ltd., Chesterford Research Park, Saffron Walden, United Kingdom (G.K.N., T.R.P.)
Gary K. Newton
Institute for Infection and Immunity, St George’s, University of London, London, United Kingdom (J.Z., J.C., C.R.); State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People’s Republic of China (J.Z.); and Domainex Ltd., Chesterford Research Park, Saffron Walden, United Kingdom (G.K.N., T.R.P.)
Trevor R. Perrior
Institute for Infection and Immunity, St George’s, University of London, London, United Kingdom (J.Z., J.C., C.R.); State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People’s Republic of China (J.Z.); and Domainex Ltd., Chesterford Research Park, Saffron Walden, United Kingdom (G.K.N., T.R.P.)
Clive Robinson
Institute for Infection and Immunity, St George’s, University of London, London, United Kingdom (J.Z., J.C., C.R.); State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, People’s Republic of China (J.Z.); and Domainex Ltd., Chesterford Research Park, Saffron Walden, United Kingdom (G.K.N., T.R.P.)
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Rapid CommunicationMinireview
Allergen Delivery Inhibitors
Jihui Zhang, Jie Chen, Gary K. Newton, Trevor R. Perrior and Clive Robinson
Molecular Pharmacology September 1, 2018, 94 (3) 1007-1030; DOI: https://doi.org/10.1124/mol.118.112730
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