An Interhelical Salt Bridge Controls Flexibility and Inhibitor Potency for Regulators of G-protein Signaling Proteins 4, 8, and 19

Vincent S. Shaw; Mohammadjavad Mohammadi; Josiah A. Quinn; Harish Vashisth; Richard R. Neubig

doi:10.1124/mol.119.117176

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An Interhelical Salt Bridge Controls Flexibility and Inhibitor Potency for Regulators of G-protein Signaling Proteins 4, 8, and 19

Vincent S. Shaw, Mohammadjavad Mohammadi, Josiah A. Quinn, Harish Vashisth and Richard R. Neubig

Molecular Pharmacology December 2019, 96 (6) 683-691; DOI: https://doi.org/10.1124/mol.119.117176

Vincent S. Shaw

Department of Pharmacology and Toxicology (V.S.S., J.A.Q., R.R.N.) and Nicholas V. Perricone, M.D., Division of Dermatology, Department of Medicine (R.R.N.), Michigan State University, East Lansing, Michigan; and Department of Chemical Engineering, University of New Hampshire, Durham, New Hampshire (M.M., H.V.)

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Mohammadjavad Mohammadi

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Josiah A. Quinn

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Harish Vashisth

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ORCID record for Harish Vashisth
For correspondence: harish.vashisth@unh.edu

Richard R. Neubig

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ORCID record for Richard R. Neubig
For correspondence: rneubig@msu.edu

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Molecular Pharmacology

Vol. 96, Issue 6

1 Dec 2019

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