Article Figures & Data
Additional Files
Data Supplement
Files in this Data Supplement:
- Figure S1 - No significant increase was detected in the weight of PDE8B KO adrenal glands compared to controls.
- Figure S2 - Trilostane, a 3betaHSD inhibitor, effectively increased pregnenolone concentration in Y-1 cells.
- Figure S3 - Transfection efficiency of shRNA plasmids.
- Figure S4 - No significant increase in PDE activity as a compensation to the reduction in PDE8B due to the chronic PDE8B ablation was found.
- Figure S5 - Chemical structure of PF-04957325.