Article Figures & Data
Additional Files
Data Supplement
Files in this Data Supplement:
- Supplemental Data -
Supplementary Table 1: Forward and reverse primer sequences used to generate the 3xHA M4 mAChR and to introduce mutations
into the M4 mAChR.
Supplementary Figure 1: Structure of ligands used in this study.
Supplementary Figure 2: D1123.32A and M4 Y1133.33A mutant receptors are expressed at the cell surface.
Supplementary Figure 3: D1123.32N reduces the binding affinity of the allosteric modulator, C7/3-phth.
- Supplemental Data -
Supplementary Table 1: Forward and reverse primer sequences used to generate the 3xHA M4 mAChR and to introduce mutations
into the M4 mAChR.