Article Figures & Data
Additional Files
Supplemental Data
Files in this Data Supplement:
- Supplemental Figures and Tables -
Figure S1 - In vitro validation of Mdr1a ZFN in rat C6 cells by Cel-1 assay.
Figure S2 - No detectable off-target cleavage detected with Mdr1a ZFN in rat genome.
Table S1 - Summary of the genotype of Mdr1a KO founders generated by ZFN injection.
Table S2 - Expression of transporter genes in brain, liver, intestine, and kidney in Mdr1a -/- and wild-type rats
Table S3 - Expression of drug metabolism related genes in brain, liver intestine and kidney of Mdr1a - /- and wild-type rats
Table S4 - Gene list of SABioscience's 384-well PCR arrays (preliminary data available upon request)
Figure S3 - SABioscience PCR array Volcano Plot (detailed preliminary data available upon request)
- Supplemental Figures and Tables -