Article Figures & Data
Additional Files
Data Supplement
Files in this Data Supplement:
- Supplemental Data -
Supplementary Figure 1 - AYPGKF-NH2 triggered calcium signaling in HEK cells transiently expressing wt-PAR4-YFP, QC-PAR4-YFP and dRS-PAR4-YFP
Supplementary Figure 2 - (A) HEK cells expressing wt or dRS-PAR4 can activate ERK and P38 MAPK signaling in response to 100-mu-M AYPGKF-NH2 treatment for 10 minutes
Supplementary Figure 3 - BRET detection of (A) Thrombin and (B) AYPGKF-NH2 triggered beta-arrestin recruitment to QC-PAR4
Supplementary Figure 4 - BRET detection of beta-arrestin1/2 recruitment to PAR2 in the presence and absence of RAG8
- Supplementary Video 1
-
FeCl3 triggered thrombosis in-vivo in SRQ8 treated control animals and RAG8 treated animals. Data are representative of three independent experiments
- Supplemental Data -