Article Figures & Data
Additional Files
Data Supplement
- Supplemental Data -
Supplemental Figure 1 - T47D-kbLuc transcriptional assays revealed 13 phytoestrogenic compounds able to transcriptionally activate ER
Supplemental Figure 2 - ICI 182,780 inhibited ER activation by flavonoid compounds in T47D-KBluc cells
Supplemental Figure 3 - Transcriptional response of selective ERα/β heterodimer inducing compounds in T47D-KBLuc transcriptional assays
Supplemental Table 1 - The statistical values of pharmacophore models after GALAHAD run
Supplemental Table 2 - Model Validation using the full compound set
Supplemental Table 3 - Top Ranked ChemBridge chemicals using SYBYLS integrated ranking features
Supplemental Table 4 - Top Ranked Maybridge chemicals using SYBYLS integrated ranking features
Supplemental Table 5 - Compounds selected for further screening
Supplemental Table 6 - 22 Compounds selected for ER dimerization BRET assays
- Supplemental Data -