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Loss-of-Function Mutations in Human Regulator of G Protein Signaling RGS2 Differentially Regulate Pharmacological Reactivity of Resistance Vasculature
Hoa T.N. Phan, William F. Jackson, Vincent S. Shaw, Stephanie W. Watts and Richard R. Neubig

Molecular Pharmacology December 2019, 96 (6) 826-834; DOI: https://doi.org/10.1124/mol.119.116822
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Conformational Changes in the 5-HT_3A Receptor Extracellular Domain Measured by Voltage-Clamp Fluorometry
Lachlan Munro, Lucy Kate Ladefoged, Vithushan Padmanathan, Signe Andersen, Birgit Schiøtt and Anders S. Kristensen

Molecular Pharmacology December 2019, 96 (6) 720-734; DOI: https://doi.org/10.1124/mol.119.116657
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The Natural Compound Withaferin A Covalently Binds to Cys239 of β-Tubulin to Promote Tubulin Degradation
Jianhong Yang, Wei Yan, Yong Li, Lu Niu, Haoyu Ye and Lijuan Chen

Molecular Pharmacology December 2019, 96 (6) 711-719; DOI: https://doi.org/10.1124/mol.119.117812
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Potential Regulation of UGT2B10 and UGT2B7 by miR-485-5p in Human Liver
Aimee K. Sutliff, Jian Shi, Christy J.W. Watson, Martina S. Hunt, Gang Chen, Hao-Jie Zhu and Philip Lazarus

Molecular Pharmacology December 2019, 96 (6) 674-682; DOI: https://doi.org/10.1124/mol.119.115881
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An Interhelical Salt Bridge Controls Flexibility and Inhibitor Potency for Regulators of G-protein Signaling Proteins 4, 8, and 19
Vincent S. Shaw, Mohammadjavad Mohammadi, Josiah A. Quinn, Harish Vashisth and Richard R. Neubig

Molecular Pharmacology December 2019, 96 (6) 683-691; DOI: https://doi.org/10.1124/mol.119.117176
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Homologous Regulation of Mu Opioid Receptor Recycling by G_βγ, Protein Kinase C, and Receptor Phosphorylation
Jennifer M. Kunselman, Amanda S. Zajac, Zara Y. Weinberg and Manojkumar A. Puthenveedu

Molecular Pharmacology December 2019, 96 (6) 702-710; DOI: https://doi.org/10.1124/mol.119.117267
Open Access
N-Terminal Modification of the Tetrapeptide Arg-Leu-Tyr-Glu, a Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) Antagonist, Improves Antitumor Activity by Increasing its Stability against Serum Peptidases
Jung-A Yun, Joohwan Kim, Yi-Yong Baek, Wonjin Park, Minsik Park, Suji Kim, Taesam Kim, Seunghwan Choi, Dooil Jeoung, Hansoo Lee, Moo-Ho Won, Ji-Yoon Kim, Kwon-Soo Ha, Young-Guen Kwon and Young-Myeong Kim

Molecular Pharmacology December 2019, 96 (6) 692-701; DOI: https://doi.org/10.1124/mol.119.117234
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Oligoarginine Peptides, a New Family of Nicotinic Acetylcholine Receptor Inhibitors
Dmitry S. Lebedev, Elena V. Kryukova, Igor A. Ivanov, Natalia S. Egorova, Nikita D. Timofeev, Ekaterina N. Spirova, Elizaveta Yu. Tufanova, Andrei E. Siniavin, Denis S. Kudryavtsev, Igor E. Kasheverov, Marios Zouridakis, Ramaz Katsarava, Nino Zavradashvili, Ia Iagorshvili, Socrates J. Tzartos and Victor I. Tsetlin

Molecular Pharmacology November 2019, 96 (5) 664-673; DOI: https://doi.org/10.1124/mol.119.117713
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The Basis for Strain-Dependent Rat Aldehyde Dehydrogenase 1A7 (ALDH1A7) Gene Expression
Katerina Touloupi, Jenni Küblbeck, Angeliki Magklara, Ferdinand Molnár, Mika Reinisalo, Maria Konstandi, Paavo Honkakoski and Periklis Pappas

Molecular Pharmacology November 2019, 96 (5) 655-663; DOI: https://doi.org/10.1124/mol.119.117424
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Induction via Functional Protein Stabilization of Hepatic Cytochromes P450 upon gp78/Autocrine Motility Factor Receptor (AMFR) Ubiquitin E3-Ligase Genetic Ablation in Mice: Therapeutic and Toxicological Relevance
Doyoung Kwon, Sung-Mi Kim, Peyton Jacob, Yi Liu and Maria Almira Correia

Molecular Pharmacology November 2019, 96 (5) 641-654; DOI: https://doi.org/10.1124/mol.119.117069

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