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Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy
Kinsie E. Arnst, Yuxi Wang, Zi-Ning Lei, Dong-Jin Hwang, Gyanendra Kumar, Dejian Ma, Deanna N. Parke, Qiang Chen, Jinliang Yang, Stephen W. White, Tiffany N. Seagroves, Zhe-Sheng Chen, Duane D. Miller and Wei Li

Molecular Pharmacology July 2019, 96 (1) 73-89; DOI: https://doi.org/10.1124/mol.118.114801
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Impact of Phosphodiesterase 4 Inhibition on the Operational Efficacy, Response Maxima, and Kinetics of Indacaterol-Induced Gene Expression Changes in BEAS-2B Airway Epithelial Cells: A Global Transcriptomic Analysis
Radhika Joshi, Dong Yan, Omar Hamed, Mahmoud M. Mostafa, Taruna Joshi, Robert Newton and Mark A. Giembycz

Molecular Pharmacology July 2019, 96 (1) 56-72; DOI: https://doi.org/10.1124/mol.118.115311
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A Small-Molecule Compound Selectively Activates K2P Channel TASK-3 by Acting at Two Distant Clusters of Residues
Fuyun Tian, Yunguang Qiu, Xi Lan, Min Li, Huaiyu Yang and Zhaobing Gao

Molecular Pharmacology July 2019, 96 (1) 26-35; DOI: https://doi.org/10.1124/mol.118.115303
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Hepatic Expression of Niemann-Pick C1-Like 1, a Cholesterol Reabsorber from Bile, Exacerbates Western Diet–Induced Atherosclerosis in LDL Receptor Mutant Mice
Hideaki Yamamoto, Yoshihide Yamanashi, Tappei Takada, Shuang Mu, Yusuke Tanaka, Toko Komine and Hiroshi Suzuki

Molecular Pharmacology July 2019, 96 (1) 47-55; DOI: https://doi.org/10.1124/mol.119.115840
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Identifying the ErbB/MAPK Signaling Cascade as a Therapeutic Target in Canine Bladder Cancer
Kathryn E. Cronise, Belen G. Hernandez, Daniel L. Gustafson and Dawn L. Duval

Molecular Pharmacology July 2019, 96 (1) 36-46; DOI: https://doi.org/10.1124/mol.119.115808
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Differential Regulation of Human Ether-à-Go-Go–Related Gene (hERG) Current and Expression by Activation of Protein Kinase C
Morgan E. Sutherland-Deveen, Tingzhong Wang, Shawn M. Lamothe, Jared N. Tschirhart, Jun Guo, Wentao Li, Tonghua Yang, Yuan Du and Shetuan Zhang

Molecular Pharmacology July 2019, 96 (1) 1-12; DOI: https://doi.org/10.1124/mol.118.115188
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Identification of MRP4/ABCC4 as a Target for Reducing the Proliferation of Pancreatic Ductal Adenocarcinoma Cells by Modulating the cAMP Efflux
Alejandro Carozzo, Agustín Yaneff, Natalia Gómez, Nicolás Di Siervi, Ana Sahores, Federico Diez, Alejandra I. Attorresi, Ángela Rodríguez-González, Federico Monczor, Natalia Fernández, Martín Abba, Carina Shayo and Carlos Davio

Molecular Pharmacology July 2019, 96 (1) 13-25; DOI: https://doi.org/10.1124/mol.118.115444
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Chemically Modified Derivatives of the Activator Compound Cloxyquin Exert Inhibitory Effect on TRESK (K_2P18.1) Background Potassium Channel
Miklós Lengyel, Ferenc Erdélyi, Enikő Pergel, Ágnes Bálint-Polonka, Alice Dobolyi, Péter Bozsaki, Mária Dux, Kornél Király, Tamás Hegedűs, Gábor Czirják, Péter Mátyus and Péter Enyedi

Molecular Pharmacology June 2019, 95 (6) 652-660; DOI: https://doi.org/10.1124/mol.118.115626
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TRESK (K2P18.1) Background Potassium Channel Is Activated by Novel-Type Protein Kinase C via Dephosphorylation
Enikő Pergel, Miklós Lengyel, Péter Enyedi and Gábor Czirják

Molecular Pharmacology June 2019, 95 (6) 661-672; DOI: https://doi.org/10.1124/mol.119.116269
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Functional CRISPR and shRNA Screens Identify Involvement of Mitochondrial Electron Transport in the Activation of Evofosfamide
Francis W. Hunter, Jules B. L. Devaux, Fanying Meng, Cho Rong Hong, Aziza Khan, Peter Tsai, Troy W. Ketela, Indumati Sharma, Purvi M. Kakadia, Stefano Marastoni, Zvi Shalev, Anthony J. R. Hickey, Cristin G. Print, Stefan K. Bohlander, Charles P. Hart, Bradly G. Wouters and William R. Wilson

Molecular Pharmacology June 2019, 95 (6) 638-651; DOI: https://doi.org/10.1124/mol.118.115196

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