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The Pore-Lipid Interface: Role of Amino-Acid Determinants of Lipophilic Access by Ivabradine to the hERG1 Pore Domain
Laura Perissinotti, Jiqing Guo, Meruyert Kudaibergenova, James Lees-Miller, Marina Ol’khovich, Angelica Sharapova, German L. Perlovich, Daniel A. Muruve, Brenda Gerull, Sergei Yu Noskov and Henry J. Duff

Molecular Pharmacology August 2019, 96 (2) 259-271; DOI: https://doi.org/10.1124/mol.118.115642
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Identification of Abundant and Evolutionarily Conserved Opioid Receptor Circular RNAs in the Nervous System Modulated by Morphine
Takeshi Irie, Rebecca Shum, Ioanna Deni, Amanda Hunkele, Valerie Le Rouzic, Jin Xu, Roger Wilson, Gregory W. Fischer, Gavril W. Pasternak and Ying-Xian Pan

Molecular Pharmacology August 2019, 96 (2) 247-258; DOI: https://doi.org/10.1124/mol.118.113977
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Pharmacological, Mechanistic, and Pharmacokinetic Assessment of Novel Melatonin-Tamoxifen Drug Conjugates as Breast Cancer Drugs
Mahmud Hasan, Mohamed Akmal Marzouk, Saugat Adhikari, Thomas D. Wright, Benton P. Miller, Margarite D. Matossian, Steven Elliott, Maryl Wright, Madlin Alzoubi, Bridgette M. Collins-Burow, Matthew E. Burow, Ulrike Holzgrabe, Darius P. Zlotos, Robert E. Stratford and Paula A. Witt-Enderby

Molecular Pharmacology August 2019, 96 (2) 272-296; DOI: https://doi.org/10.1124/mol.119.116202
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Modulation of Burst Firing of Neurons in Nucleus Reticularis of the Thalamus by GluN2C-Containing NMDA Receptors
Jinxu Liu, Gajanan P. Shelkar, Fabao Zhao, Rasmus P. Clausen and Shashank M. Dravid

Molecular Pharmacology August 2019, 96 (2) 193-203; DOI: https://doi.org/10.1124/mol.119.116780
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Nonclassical Ligand-Independent Regulation of Go Protein by an Orphan Class C G-Protein–Coupled Receptor
Mariana Hajj, Teresa De Vita, Claire Vol, Charlotte Renassia, Jean-Charles Bologna, Isabelle Brabet, Magali Cazade, Manuela Pastore, Jaroslav Blahos, Gilles Labesse, Jean-Philippe Pin and Laurent Prézeau

Molecular Pharmacology August 2019, 96 (2) 233-246; DOI: https://doi.org/10.1124/mol.118.113019
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Insights into Doxorubicin-induced Cardiotoxicity: Molecular Mechanisms, Preventive Strategies, and Early Monitoring
Nadine Wenningmann, Merle Knapp, Anusha Ande, Tanaya R. Vaidya and Sihem Ait-Oudhia

Molecular Pharmacology August 2019, 96 (2) 219-232; DOI: https://doi.org/10.1124/mol.119.115725
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Identification of Serine-875 as an Inhibitory Phosphorylation Site in the Calcium-Sensing Receptor
Lenah S. Binmahfouz, Patricia P. Centeno, Arthur D. Conigrave and Donald T. Ward

Molecular Pharmacology August 2019, 96 (2) 204-211; DOI: https://doi.org/10.1124/mol.119.116178
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Binding Interactions of NS6740, a Silent Agonist of the α7 Nicotinic Acetylcholine Receptor
Catriona E. W. Blunt and Dennis A. Dougherty

Molecular Pharmacology August 2019, 96 (2) 212-218; DOI: https://doi.org/10.1124/mol.119.116244
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Severe Hepatotoxicity of Mithramycin Therapy Caused by Altered Expression of Hepatocellular Bile Transporters
Tristan M. Sissung, Phoebe A. Huang, Ralph J. Hauke, Edel M. McCrea, Cody J. Peer, Roberto H. Barbier, Jonathan D. Strope, Ariel M. Ley, Mary Zhang, Julie A. Hong, David Venzon, Jonathan P. Jackson, Kenneth R. Brouwer, Patrick Grohar, Jon Glod, Brigitte C. Widemann, Theo Heller, David S. Schrump and William D. Figg

Molecular Pharmacology August 2019, 96 (2) 158-167; DOI: https://doi.org/10.1124/mol.118.114827
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Inhibition of Heat Shock Protein 90 suppresses TWIST1 Transcription
Kay Yi Chong, Min Kang, Francesca Garofalo, Daiki Ueno, Huamao Liang, Sarah Cady, Oluwagbemisola Madarikan, Nicholas Pitruzzello, Cheng-Hsiu Tsai, Tobias M.P. Hartwich, Brian M. Shuch and Yang Yang-Hartwich

Molecular Pharmacology August 2019, 96 (2) 168-179; DOI: https://doi.org/10.1124/mol.119.116137

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