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G Protein–Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands
Nikoleta G. Tsvetanova, Michelle Trester-Zedlitz, Billy W. Newton, Daniel P. Riordan, Aparna B. Sundaram, Jeffrey R. Johnson, Nevan J. Krogan and Mark von Zastrow

Molecular Pharmacology February 2017, 91 (2) 145-156; DOI: https://doi.org/10.1124/mol.116.106369
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Homobivalent Conjugation Increases the Allosteric Effect of 9-aminoacridine at the α₁-Adrenergic Receptors
Adrian P. Campbell, Laurence P. G. Wakelin, William A. Denny and Angela M. Finch

Molecular Pharmacology February 2017, 91 (2) 135-144; DOI: https://doi.org/10.1124/mol.116.105874
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Dynamin Functions and Ligands: Classical Mechanisms Behind
Mahaveer Singh, Hemant R. Jadhav and Tanya Bhatt

Molecular Pharmacology February 2017, 91 (2) 123-134; DOI: https://doi.org/10.1124/mol.116.105064
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The E Loop of the Transmitter Binding Site Is a Key Determinant of the Modulatory Effects of Physostigmine on Neuronal Nicotinic α4β2 Receptors
Xiaochun Jin, Megan M. McCollum, Allison L. Germann, Gustav Akk and Joe Henry Steinbach

Molecular Pharmacology February 2017, 91 (2) 100-109; DOI: https://doi.org/10.1124/mol.116.106484
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Orally Administered Berberine Modulates Hepatic Lipid Metabolism by Altering Microbial Bile Acid Metabolism and the Intestinal FXR Signaling Pathway
Runbin Sun, Na Yang, Bo Kong, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Jingqiu Huang, Jianliang Shen, Pei Wang, Siqi Feng, Fei Fei, Jiahua Guo, Jun He, Nan Aa, Qiang Chen, Yang Pan, Justin D. Schumacher, Chung S. Yang, Grace L. Guo, Jiye Aa and Guangji Wang

Molecular Pharmacology February 2017, 91 (2) 110-122; DOI: https://doi.org/10.1124/mol.116.106617
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Cannabinoid Receptor Interacting Protein 1a Competition with β-Arrestin for CB₁ Receptor Binding Sites
Lawrence C. Blume, Theresa Patten, Khalil Eldeeb, Sandra Leone-Kabler, Alexander A. Ilyasov, Bradley M. Keegan, Jeremy E. O’Neal, Caroline E. Bass, Roy R. Hantgan, W. Todd Lowther, Dana E. Selley and Allyn C. Howlett

Molecular Pharmacology February 2017, 91 (2) 75-86; DOI: https://doi.org/10.1124/mol.116.104638
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Isoform-Specific Biased Agonism of Histamine H₃ Receptor Agonists
Darren M. Riddy, Anna E. Cook, Natalie A. Diepenhorst, Sanja Bosnyak, Ryan Brady, Clotilde Mannoury la Cour, Elisabeth Mocaer, Roger J. Summers, William N. Charman, Patrick M. Sexton, Arthur Christopoulos and Christopher J. Langmead

Molecular Pharmacology February 2017, 91 (2) 87-99; DOI: https://doi.org/10.1124/mol.116.106153
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Editor's Note
Kathryn E. Meier

Molecular Pharmacology January 2017, 91 (1) 74; DOI: https://doi.org/10.1124/mol.116.107961
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Non-cell-autonomous Effects of Autophagy Inhibition in Tumor Cells Promote Growth of Drug-resistant Cells
Jacqueline Thorburn, Leah Staskiewicz, Megan L. Goodall, Lina Dimberg, Arthur E. Frankel, Heide L. Ford and Andrew Thorburn

Molecular Pharmacology January 2017, 91 (1) 58-64; DOI: https://doi.org/10.1124/mol.116.106070
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Endosomal Phosphatidylinositol 3-Kinase Is Essential for Canonical GPCR Signaling
Yasunori Uchida, Florentine U. Rutaganira, Damien Jullié, Kevan M. Shokat and Mark von Zastrow

Molecular Pharmacology January 2017, 91 (1) 65-73; DOI: https://doi.org/10.1124/mol.116.106252

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