POINT MUTATIONS IN EITHER SUBUNIT OF THE GABAB RECEPTOR CONFER CONSTITUTIVE ACTIVITY TO THE HETERODIMER

Data Supplement

Files in this Data Supplement:

• Data Supplement - Supplemental Fig. 1. Multiple alignment comparing the deduced amino acid sequence of the mouse, rat and human GABABR2.
• Data Supplement - Supplemental Fig. 2. The R1 (N179K) and R2 (A803V) mutants do not show an elevation in basal signaling.
• Data Supplement - Supplemental Table 1: Sequences of primers used to amplify the mouse GABAB receptor R1 and R2 subunits.