Discovery of a highly active ligand of human Pregnane X Receptor: a case study from pharmacophore modeling and virtual screening to "in vivo" biological activity

Data Supplement

Files in this Data Supplement:

• Data Supplement - Figure 1. Position of rifampicin in the ligand binding pocket of hPXR...
• Data Supplement - Figure 2. Table A, Set I. Docking results of compounds described in this manuscript.
  Table B. Set II. Docking results of 10 additional compounds...
• Data Supplement - Figure 3. C2B4-A is an efficient hPXR agonist...
• Data Supplement - Figure 4. Effect of C2B4-A on an in vivo induction of hPXR in nude mice...