High mobility group protein B1 is an activator of apoptotic response to antimetabolite drugs

Data Supplement

Files in this Data Supplement:

  • Data Supplement - Fig. S1. Dose-response curves for Hmgb1+/+ (dashed lines) and Hmgb1-/- (solid lines) MEFs treated with a panel of antimetabolite drugs over the following range of concentrations...
  • Data Supplement - Fig. S2. Incorporation of radiolabeled nucleoside analogs into genomic DNA in Hmgb1+/+ (smooth bars) and Hmgb1-/- (striped bars) cells. 3H-araC or 14C-MP were incubated with cells for 14-28 hr, and DNA extracted from the cells was quantified and counted as described in Materials and Methods.
  • Data Supplement - Fig. S3. Western blot analysis of activated ATM (phosphorylated at serine 1981) and ATR in Hmgb1+/+ (open bars) and Hmgb1-/- (filled bars) cells following treatment with 10 �M MP for 14-42 hFig. S3. Western blot analysis of activated ATM (phosphorylated at serine 1981) and ATR in Hmgb1+/+ (open bars) and Hmgb1-/- (filled bars) cells following treatment with 10 μM MP for 14-42 hr...
  • Data Supplement - Table S1. The complete list of discriminative genes between Hmgb1+/+ and Hmgb1-/- MEFs.
  • Data Supplement - Complete Legends

This Article

  1. Published online before print October 19, 2007, doi: 10.1124/mol.107.041764
  1. Full Text (PDF)
  2. » Data Supplement

Current Issue

  1. November 2009, 76 (5)
  1. Current Issue
  1. Alert me to new issues of Molecular Pharmacology