Lipid composition alters drug action at the nicotinic acetylcholine receptor

Data Supplement

Files in this Data Supplement:

  • Data Supplement - Table 1S. Statistical Analysis of the Curve Fitting of the Band Intensity Changes Observed at Different Frequencies in the Difference Spectra Recorded from the nAChR in the Presence of the Local Anesthetics Tetracaine and Procaine.
  • Data Supplement - Fig.1S. Schematic diagram of the data acquisition protocol...
  • Data Supplement - Fig.2S. The increase in intensity leads to a separate positive peak centered near 1663 cm-1...
  • Data Supplement - Fig.3S. Superimposition of the spectra shows that no dose dependent increase in intensity of any of the amide I or amide II difference bands indicative of desensitization can be detected...
  • Data Supplement - Fig.4S. The increase in intensity near 1663 cm-1 is clearly visible in spectra recorded at...
  • Data Supplement - Fig.5S. Carb difference spectra recorded from the nAChR in PC/Chol 3:2...

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