Rapamycin inhibits polyglutamine aggregation independently of autophagy by reducing protein synthesis

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  Fig S1. Atg5+/+ and Atg5-/- cells are transfected with similar efficiencies...
  Fig S2. The amount of SDS-insoluble Ex1HttQ97-EGFP is similarly reduced by rapamycin in Atg5+/+ and Atg5-/- cells...
  Fig S3. Inhibition of cell number and total cellular protein induced by rapamycin...
  Fig S4. Overexpressed Atg5 associates with IBs and is found in the insoluble protein fraction...
  Fig S5. Between 0.01-0.03 Μg/ml, CHX suppresses formation of SDS-insoluble Ex1HttQ97-EGFP, steady state cellular protein concentration and IBs similarly to 200 nM rapamycin in both Atg5+/+ and Atg-/- MEFs...