GITR-FC FUSION PROTEIN INHIBITS GITR TRIGGERING AND PROTECTS FROM THE INFLAMMATORY RESPONSE FOLLOWING SPINAL CORD INJURY

Data Supplement

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• Data Supplement -
  Figure s1.Lower expression of IL-12 in the spinal cord of SCI-GITR-/-mice and SCI-GITR+/+ mice treated with GITR-Fc as compared to SCI-GITR+/+ mice.
  Figure s2. Lower expression of TNF-alpha in the spinal cord of SCI-GITR-/-mice and SCI-GITR+/+ mice treated with GITR-Fc as compared to SCI-GITR+/+ mice.
  Figure s3. Less apoptotic cells in the spinal cord of SCI-GITR-/-mice and SCI-GITR+/+ mice treated with GITR-Fc as compared to SCI-GITR+/+ mice.
  Figure s4. Lower expression of FasL in the spinal cord of SCI-GITR-/-mice and SCI-GITR+/+mice treated with GITR-Fc as compared to SCI-GITR+/+mice.
  Figure s5. Lower expression of Bax in the spinal cord of SCI-GITR-/-mice and SCI-GITR+/+ mice treated with GITR-Fc as compared to SCI-GITR+/+ mice.
  Figure s6. Higher expression of Bcl-2 in the spinal cord of SCI-GITR-/-mice and SCI-GITR+/+ mice treated with GITR-Fc as compared to SCI-GITR+/+ mice.