Data Supplement
Files in this Data Supplement:
- Data Supplement -
Supplemental Figure 1 - Selectivity of Nb80 for agonist-occupied beta-2AR determined by ELIS
Supplemental Figure 2 - Active beta-2AR conformational states can be detected using the radioligand 3HMethoxyfenoterol
Supplemental Figure 3 - Nanobodies bind to epitopes on intracellular surface of the beta-2AR
Supplemental Figure 4 - Assays used to measure G-protein activation (cAMP-GloSensor) and beta-arrestin recruitment (Tango) display similar levels of signal amplification