Correctors of the major Cystic Fibrosis mutant interact through membrane spanning domains

Data Supplement

• Supplemental Figures -

  Supplemental Figure 1 - C4 stabilizes MSD2-NBD2 of CFTR
  

  Supplemental Figure 2 - Additive effect of VX-809 and C4 on processing of R170G-CFTR

  Supplemental Figure 3 - VX-809, C4 and glycerol correction of F508del-CFTR is additive with the R1070W second-site mutation