Mol Pharm -- Table of Contents (51 [3])

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March 1997; 51 (3)   [Index by Author] [Cover Caption]

       Accelerated Communication

       Articles

       Errata

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Accelerated Communication:

B. F. Roettger, D. Ghanekar, R. Rao, C. Toledo, J. Yingling, D. Pinon, and L. J. Miller: Antagonist-Stimulated Internalization of the G Protein-Coupled Cholecystokinin Receptor
Mol Pharmacol 1997 51: 357-362. [Abstract] [Full Text] [PDF]

Articles:

Felix W. Frueh, Ulrich M. Zanger, and Urs A. Meyer: Extent and Character of Phenobarbital-Mediated Changes in Gene Expression in the Liver
Mol Pharmacol 1997 51: 363-369. [Abstract] [Full Text] [PDF]

Yin Hu, Mikael Oscarson, Inger Johansson, Qun-Ying Yue, Marja-Liisa Dahl, Marco Tabone, Sarino Arincò, Emanuele Albano, and Magnus Ingelman-Sundberg: Genetic Polymorphism of Human CYP2E1: Characterization of Two Variant Alleles
Mol Pharmacol 1997 51: 370-376. [Abstract] [Full Text] [PDF]

Ricardo I. Monzon, Catherine Fillmore, and Laurie G. Hudson: Functional Consequences of Reduced Retinoic Acid Receptor $gamma$ Expression in a Human Squamous Cell Carcinoma Line
Mol Pharmacol 1997 51: 377-382. [Abstract] [Full Text] [PDF]

Catherine L. Cioffi, Michelle Garay, Joseph F. Johnston, Kathy McGraw, Russell T. Boggs, David Hreniuk, and Brett P. Monia: Selective Inhibition of A-Raf and C-Raf mRNA Expression by Antisense Oligodeoxynucleotides in Rat Vascular Smooth Muscle Cells: Role of A-Raf and C-Raf in Serum-Induced Proliferation
Mol Pharmacol 1997 51: 383-389. [Abstract] [Full Text] [PDF]

Wen-Mei Fu and Jiunn-Jiun Liu: Regulation of Acetylcholine Release by Presynaptic Nicotinic Receptors at Developing Neuromuscular Synapses
Mol Pharmacol 1997 51: 390-398. [Abstract] [Full Text] [PDF]

Tomoyuki Sumizawa, Zhe-Sheng Chen, Yutaka Chuman, Kiyotomo Seto, Tatsuhiko Furukawa, Misako Haraguchi, Ayako Tani, Norimasa Shudo, and Shin-Ichi Akiyama: Reversal of Multidrug Resistance-Associated Protein-Mediated Drug Resistance by the Pyridine Analog PAK-104P
Mol Pharmacol 1997 51: 399-405. [Abstract] [Full Text] [PDF]

Claire Senay, Mohamed Ouzzine, Eric Battaglia, Dorothy Pless, Virginie Cano, Brian Burchell, Anna Radominska, Jacques Magdalou, and Sylvie Fournel-Gigleux: Arginine 52 and Histidine 54 Located in a Conserved Amino-Terminal Hydrophobic Region (LX2-R52-G-H54-X3-V-L) Are Important Amino Acids for the Functional and Structural Integrity of the Human Liver UDP-Glucuronosyltransferase UGT1*6
Mol Pharmacol 1997 51: 406-413. [Abstract] [Full Text] [PDF]

Sonsoles Hortelano and Lisardo Boscá: 6-Mercaptopurine Decreases the Bcl-2/Bax Ratio and Induces Apoptosis in Activated Splenic B Lymphocytes
Mol Pharmacol 1997 51: 414-421. [Abstract] [Full Text] [PDF]

Kang-Shen Yao, Alexandre Hageboutros, Patricia Ford, and Peter J. O'Dwyer: Involvement of Activator Protein-1 and Nuclear Factor- $kappa$ B Transcription Factors in the Control of the DT-Diaphorase Expression Induced by Mitomycin C Treatment
Mol Pharmacol 1997 51: 422-430. [Abstract] [Full Text] [PDF]

Chantal Pichon, Khalil Arar, Alistair J. Stewart, Madeleine Duc Dodon, Louis Gazzolo, Pierre J. Courtoy, Roger Mayer, Michel Monsigny, and Annie-Claude Roche: Intracellular Routing and Inhibitory Activity of Oligonucleopeptides Containing a KDEL Motif
Mol Pharmacol 1997 51: 431-438. [Abstract] [Full Text] [PDF]

Hyeon-Woo Lee, Lucinda Smith, George R. Pettit, and Jeffrey Bingham Smith: Bryostatin 1 and Phorbol Ester Down-Modulate Protein Kinase C- $alpha$ and - $epsilon$ via the Ubiquitin/Proteasome Pathway in Human Fibroblasts
Mol Pharmacol 1997 51: 439-447. [Abstract] [Full Text] [PDF]

Jean-Pierre Henichart, Michael J. Waring, Jean-Francois Riou, William A. Denny, and Christian Bailly: Copper-Dependent Oxidative and Topoisomerase II-Mediated DNA Cleavage by a Netropsin/4 $'$ -(9-acridinylamino)methanesulfon-m-anisidide Combilexin
Mol Pharmacol 1997 51: 448-461. [Abstract] [Full Text] [PDF]

Uy Dong Sohn, Driss Zoukhri, Darlene Dartt, Christian Sergheraert, Karen M. Harnett, Jose Behar, and Piero Biancani: Different Protein Kinase C Isozymes Mediate Lower Esophageal Sphincter Tone and Phasic Contraction of Esophageal Circular Smooth Muscle
Mol Pharmacol 1997 51: 462-470. [Abstract] [Full Text] [PDF]

Toshiyuki Matsuoka, Tomoyuki Nishizaki, and Kimiaki Sumino: A Specific Inhibitory Action of Lithium on the 5-HT_2c Receptor Expressed in Xenopus laevis Oocytes
Mol Pharmacol 1997 51: 471-474. [Abstract] [Full Text] [PDF]

A. A. Elliott and J. R. Elliott: Voltage-Dependent Inhibition of RCK1 K⁺ Channels by Phenol, p-Cresol, and Benzyl Alcohol
Mol Pharmacol 1997 51: 475-483. [Abstract] [Full Text] [PDF]

Enrico Sanna, Antonella Murgia, Anna Casula, and Giovanni Biggio: Differential Subunit Dependence of the Actions of the General Anesthetics Alphaxalone and Etomidate at $gamma$ -Aminobutyric Acid Type A Receptors Expressed in Xenopus laevis Oocytes
Mol Pharmacol 1997 51: 484-490. [Abstract] [Full Text] [PDF]

Michael C. Sanguinetti, Janice H. Johnson, Lance G. Hammerland, Paul R. Kelbaugh, Robert A. Volkmann, Nicholas A. Saccomano, and Alan L. Mueller: Heteropodatoxins: Peptides Isolated from Spider Venom that Block Kv4.2 Potassium Channels
Mol Pharmacol 1997 51: 491-498. [Abstract] [Full Text] [PDF]

M. Quik, J. Philie, and J. Choremis: Modulation of $alpha$ 7 Nicotinic Receptor-Mediated Calcium Influx by Nicotinic Agonists
Mol Pharmacol 1997 51: 499-506. [Abstract] [Full Text] [PDF]

Sharon L. Ripp, Lila H. Overby, Richard M. Philpot, and Adnan A. Elfarra: Oxidation of Cysteine S-Conjugates by Rabbit Liver Microsomes and cDNA-Expressed Flavin-Containing Mono-oxygenases: Studies with S-(1,2-Dichlorovinyl)-L-cysteine, S-(1,2,2-Trichlorovinyl)-L-cysteine, S-Allyl-L-cysteine, and S-Benzyl-L-cysteine
Mol Pharmacol 1997 51: 507-515. [Abstract] [Full Text] [PDF]

V. Casavola, L. Guerra, S. J. Reshkin, K. A. Jacobson, and H. Murer: Polarization of Adenosine Effects on Intracellular pH in A₆ Renal Epithelial Cells
Mol Pharmacol 1997 51: 516-523. [Abstract] [Full Text] [PDF]

Anton D. Michel, Kerry J. Miller, Kenneth Lundström, Gary N. Buell, and Patrick P.A. Humphrey: Radiolabeling of the Rat P2X₄ Purinoceptor: Evidence for Allosteric Interactions of Purinoceptor Antagonists and Monovalent Cations with P2X Purinoceptors
Mol Pharmacol 1997 51: 524-532. [Abstract] [Full Text] [PDF]

Errata:

: Correction for vol. 50, p. 1000
Mol Pharmacol 1997 51: 1. [Full Text]

Cover Caption:

About the cover: Stereo view of the proposed interaction between the neuropeptide Y Y₁ receptor and a nonpeptide analog ofthe carboxyl-terminal four amino acids of neuropeptide Y. Thehelices of the human Y₁ receptor are shown in yellow ribbon, andthe side chains of the binding site are shown in yellow. The nonpeptideanalog BIB 3226 is colored by atom type (green, carbon; red, oxygen;blue, nitrogen; white, hydrogen). The model was derived by comparisonof the affinity of neuropeptide Y and BIB 3226 to a large numberof Y₁ receptor mutants expressed in HeLa cells. From Sautel, M.,K. Rudolph, H. Wittneben, H. Herzog, R. Martinez, M. Munoz, W.Eberlein, W. Engel, P. Walker, A. G. Beck-Sickinger. NeuropeptideY and the nonpeptide antagonist BIBP 3226 share an overlappingbinding siteatthe human Y1 receptor. Mol. Pharmacol. 50:285-292(1996).