Mol Pharm -- Table of Contents (51 [4])

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April 1997; 51 (4)   [Index by Author] [Cover Caption]

       Accelerated Communication

       Articles

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Accelerated Communication:

Christian Behl, Thomas Skutella, Frank Lezoualc'H, Anke Post, Martina Widmann, Christopher J. Newton, and Florian Holsboer: Neuroprotection against Oxidative Stress by Estrogens: Structure-Activity Relationship
Mol Pharmacol 1997 51: 535-541. [Abstract] [Full Text] [PDF]

Articles:

Ryoichi Ishitani, Katsuyoshi Sunaga, Masaharu Tanaka, Hideki Aishita, and De-Maw Chuang: Overexpression of Glyceraldehyde-3-Phosphate Dehydrogenase Is Involved in Low K⁺-Induced Apoptosis but Not Necrosis of Cultured Cerebellar Granule Cells
Mol Pharmacol 1997 51: 542-550. [Abstract] [Full Text] [PDF]

Steven L. Coon, Susan K. McCune, David Sugden, and David C. Klein: Regulation of Pineal $alpha$ _1B-Adrenergic Receptor mRNA: Day/Night Rhythm and $beta$ -Adrenergic Receptor/Cyclic AMP Control
Mol Pharmacol 1997 51: 551-557. [Abstract] [Full Text] [PDF]

Mei-Chih Wang, Jin Huang Liu, and Fung-Fang Wang: Protein Tyrosine Phosphatase-Dependent Activation of $beta$ -Globin and $delta$ -Aminolevulinic Acid Synthase Genes in the Camptothecin-Induced IW32 Erythroleukemia Cell Differentiation
Mol Pharmacol 1997 51: 558-566. [Abstract] [Full Text] [PDF]

Abhijit Mazumder, Hiroyuki Uchida, Nouri Neamati, Sanjay Sunder, Maria Jaworska-Maslanka, Eric Wickstrom, Fan Zeng, Roger A. Jones, Robert F. Mandes, H. Keith Chenault, and Yves Pommier: Probing Interactions between Viral DNA and Human Immunodeficiency Virus Type 1 Integrase Using Dinucleotides
Mol Pharmacol 1997 51: 567-575. [Abstract] [Full Text] [PDF]

Christine Reichel, Roland Brugger, Holger Bang, Gerd Geisslinger, and Kay Brune: Molecular Cloning and Expression of a 2-Arylpropionyl-Coenzyme A Epimerase: A Key Enzyme in the Inversion Metabolism of Ibuprofen
Mol Pharmacol 1997 51: 576-582. [Abstract] [Full Text] [PDF]

Ying-Chun Cai, Lan Ma, Guo-Huang Fan, Jing Zhao, Li-Zhen Jiang, and Gang Pei: Activation of N-Methyl-D-Aspartate Receptor Attenuates Acute Responsiveness of $delta$ -Opioid Receptors
Mol Pharmacol 1997 51: 583-587. [Abstract] [Full Text] [PDF]

Gregg E. Homanics, Carolyn Ferguson, Joseph J. Quinlan, Jodi Daggett, Kimberly Snyder, Carl Lagenaur, Zhi-Ping Mi, Xiao-Hui Wang, Dennis R. Grayson, and Leonard L. Firestone: Gene Knockout of the $alpha$ 6 Subunit of the $gamma$ -Aminobutyric Acid Type A Receptor: Lack of Effect on Responses to Ethanol, Pentobarbital, and General Anesthetics
Mol Pharmacol 1997 51: 588-596. [Abstract] [Full Text] [PDF]

Sulaiman Sheriff, William. T. Chance, Josef. E. Fischer, and Ambikaipakan Balasubramaniam: Neuropeptide Y Treatment and Food Deprivation Increase Cyclic AMP Response Element-Binding in Rat Hypothalamus
Mol Pharmacol 1997 51: 597-604. [Abstract] [Full Text] [PDF]

Andre H. Lagrange, Oline K. Rønnekleiv, and Martin J. Kelly: Modulation of G Protein-Coupled Receptors by an Estrogen Receptor that Activates Protein Kinase A
Mol Pharmacol 1997 51: 605-612. [Abstract] [Full Text] [PDF]

Patricia Hentosh and Martin Tibudan: 2-Chloro-2 $'$ -deoxyadenosine, an Antileukemic Drug, Has an Early Effect on Cellular Mitochondrial Function
Mol Pharmacol 1997 51: 613-619. [Abstract] [Full Text] [PDF]

Suleiman W. Bahouth, Xiaoli Cui, Michael J. Beauchamp, Hiromi Shimomura, Shaji T. George, and Edwards A. Park: Promoter Analysis of the Rat $beta$ ₁-Adrenergic Receptor Gene Identifies Sequences Involved in Basal Expression
Mol Pharmacol 1997 51: 620-629. [Abstract] [Full Text] [PDF]

Ming-Biao Yin, Wieland Voigt, Angeles Panadero, Udo Vanhoefer, Cheryl Frank, Sanja Pajovic, Jane Azizkhan, and Youcef M. Rustum: p53 and WAF1 Are Induced and Rb Protein Is Hypophosphorylated during Cell Growth Inhibition by the Thymidylate Synthase Inhibitor ZD1694 (Tomudex)
Mol Pharmacol 1997 51: 630-636. [Abstract] [Full Text] [PDF]

C. Gargalidis-Moudanos, A. Remaury, N. Pizzinat, and A. Parini: Predominant Expression of Monoamine Oxidase B Isoform in Rabbit Renal Proximal Tubule: Regulation By I₂ Imidazoline Ligands in Intact Cells
Mol Pharmacol 1997 51: 637-643. [Abstract] [Full Text] [PDF]

James G. Granneman, Ying Zhai, and Kristine N. Lahners: Selective Up-Regulation of $alpha$ _1a-Adrenergic Receptor Protein and mRNA in Brown Adipose Tissue by Neural and $beta$ ₃-Adrenergic Stimulation
Mol Pharmacol 1997 51: 644-650. [Abstract] [Full Text] [PDF]

Vera L. Trainer, Jancy C. Mcphee, Helene Boutelet-Bochan, Carl Baker, Todd Scheuer, Didier Babin, Jean-Pierre Demoute, Denis Guedin, and William A. Catterall: High Affinity Binding of Pyrethroids to the $alpha$ Subunit of Brain Sodium Channels
Mol Pharmacol 1997 51: 651-657. [Abstract] [Full Text] [PDF]

Gordana Pozvek, Joanne M. Hilton, Maribel Quiza, Souheir Houssami, and Patrick M. Sexton: Structure/Function Relationships of Calcitonin Analogues as Agonists, Antagonists, or Inverse Agonists in a Constitutively Activated Receptor Cell System
Mol Pharmacol 1997 51: 658-665. [Abstract] [Full Text] [PDF]

Joanne J. Chen, Julia Dymshitz, and Michael R. Vasko: Regulation of Opioid Receptors in Rat Sensory Neurons in Culture
Mol Pharmacol 1997 51: 666-673. [Abstract] [Full Text] [PDF]

Christian Tränkle and Klaus Mohr: Divergent Modes of Action among Cationic Allosteric Modulators of Muscarinic M₂ Receptors
Mol Pharmacol 1997 51: 674-682. [Abstract] [Full Text] [PDF]

H. Criss Hartzell, Khaled Machaca, and Yoshiyuki Hirayama: Effects of Adenophostin-A and Inositol-1,4,5-trisphosphate on Cl Currents in Xenopus laevis Oocytes
Mol Pharmacol 1997 51: 683-692. [Abstract] [Full Text] [PDF]

Cover Caption:

About the cover: Stereo view of the proposed interaction between the neuropeptide Y Y₁ receptor and a nonpeptide analog ofthe carboxyl-terminal four amino acids of neuropeptide Y. Thehelices of the human Y₁ receptor are shown in yellow ribbon, andthe side chains of the binding site are shown in yellow. The nonpeptideanalog BIB 3226 is colored by atom type (green, carbon; red, oxygen;blue, nitrogen; white, hydrogen). The model was derived by comparisonof the affinity of neuropeptide Y and BIB 3226 to a large numberof Y₁ receptor mutants expressed in HeLa cells. From Sautel, M.,K. Rudolph, H. Wittneben, H. Herzog, R. Martinez, M. Munoz, W.Eberlein, W. Engel, P. Walker, A. G. Beck-Sickinger. NeuropeptideY and the nonpeptide antagonist BIBP 3226 share an overlappingbinding siteatthe human Y1 receptor. Mol. Pharmacol. 50:285-292(1996).