Mol Pharm -- Table of Contents (51 [5])

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May 1997; 51 (5)   [Index by Author] [Cover Caption]

       Accelerated Communication

       Articles

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Accelerated Communication:

Patty W. Wong and Isaac N. Pessah: Noncoplanar PCB 95 Alters Microsomal Calcium Transport by an Immunophilin FKBP12-Dependent Mechanism
Mol Pharmacol 1997 51: 693-702. [Abstract] [Full Text] [PDF]

Articles:

Olaf Döhr, Ralf Sinning, Christoph Vogel, Peter Münzel, and Josef Abel: Effect of Transforming Growth Factor- $beta$ ₁ on Expression of Aryl Hydrocarbon Receptor and Genes of Ah Gene Battery: Clues for Independent Down-Regulation in A549 Cells
Mol Pharmacol 1997 51: 703-710. [Abstract] [Full Text] [PDF]

David A. Daunt, Carl Hurt, Lutz Hein, Jaana Kallio, Felix Feng, and Brian K. Kobilka: Subtype-Specific Intracellular Trafficking of $alpha$ ₂-Adrenergic Receptors
Mol Pharmacol 1997 51: 711-720. [Abstract] [Full Text] [PDF]

Takaharu Tsuda, Takashi Kusui, Wei Hou, Richard V. Benya, Mark A. Akeson, Glenn S. Kroog, James F. Battey, and Robert T. Jensen: Effect of Gastrin-Releasing Peptide Receptor Number on Receptor Affinity, Coupling, Degradation, and Modulation
Mol Pharmacol 1997 51: 721-732. [Abstract] [Full Text] [PDF]

L. Judson Chandler, Greg Sutton, Dean Norwood, Colin Sumners, and Fulton T. Crews: Chronic Ethanol Increases N-Methyl-D-Aspartate-Stimulated Nitric Oxide Formation but Not Receptor Density in Cultured Cortical Neurons
Mol Pharmacol 1997 51: 733-740. [Abstract] [Full Text] [PDF]

Phyllissa Schmiedlin-Ren, Kenneth E. Thummel, Jeannine M. Fisher, Mary F. Paine, Kenneth S. Lown, and Paul B. Watkins: Expression of Enzymatically Active CYP3A4 by Caco-2 Cells Grown on Extracellular Matrix-Coated Permeable Supports in the Presence of 1 $alpha$ ,25-Dihydroxyvitamin D₃
Mol Pharmacol 1997 51: 741-754. [Abstract] [Full Text] [PDF]

José J. Lucas, Louis Segu, and René Hen: 5-Hydroxytryptamine_1B Receptors Modulate the Effect of Cocaine on c-fos Expression: Converging Evidence Using 5-Hydroxytryptamine_1B Knockout Mice and the 5-Hydroxytryptamine_1B/1D Antagonist GR127935
Mol Pharmacol 1997 51: 755-763. [Abstract] [Full Text] [PDF]

Xiaohua Xin, Nengyu Yang, Andrea D. Eckhart, and James E. Faber: $alpha$ _1D-Adrenergic Receptors and Mitogen-Activated Protein Kinase Mediate Increased Protein Synthesis by Arterial Smooth Muscle
Mol Pharmacol 1997 51: 764-775. [Abstract] [Full Text] [PDF]

Xiao Peng, Volodymyr Gerzanich, René Anand, Fan Wang, and Jon Lindstrom: Chronic Nicotine Treatment Up-Regulates $alpha$ 3 and $alpha$ 7 Acetylcholine Receptor Subtypes Expressed by the Human Neuroblastoma Cell Line SH-SY5Y
Mol Pharmacol 1997 51: 776-784. [Abstract] [Full Text] [PDF]

Run Yu and Patricia M. Hinkle: Effect of Cell Type on the Subcellular Localization of the Thyrotropin-Releasing Hormone Receptor
Mol Pharmacol 1997 51: 785-793. [Abstract] [Full Text] [PDF]

Philip A. Iredale and Ronald S. Duman: Glucocorticoid Regulation of Corticotropin-Releasing Factor₁ Receptor Expression in Pituitary-Derived AtT-20 Cells
Mol Pharmacol 1997 51: 794-799. [Abstract] [Full Text] [PDF]

Luc Ménard, Stephen S. G. Ferguson, Jie Zhang, Fang-Tsyr Lin, Robert J. Lefkowitz, Marc G. Caron, and Larry S. Barak: Synergistic Regulation of $beta$ ₂-Adrenergic Receptor Sequestration: Intracellular Complement of $beta$ -Adrenergic Receptor Kinase and $beta$ -Arrestin Determine Kinetics of Internalization
Mol Pharmacol 1997 51: 800-808. [Abstract] [Full Text] [PDF]

Robert J. Vandenberg, Ann D. Mitrovic, Mary Chebib, Vladimir J. Balcar, and Graham A. R. Johnston: Contrasting Modes of Action of Methylglutamate Derivatives on the Excitatory Amino Acid Transporters, EAAT1 and EAAT2
Mol Pharmacol 1997 51: 809-815. [Abstract] [Full Text] [PDF]

Ali Ardati, Robert A. Henningsen, Jacqueline Higelin, Rainer K. Reinscheid, Olivier Civelli, and Frederick J. Monsma, Jr.: Interaction of [³H]Orphanin FQ and ¹²⁵I-Tyr14-Orphanin FQ with the Orphanin FQ Receptor: Kinetics and Modulation by Cations and Guanine Nucleotides
Mol Pharmacol 1997 51: 816-824. [Abstract] [Full Text] [PDF]

Mark C. Waltham, Wei-Wei Li, Helena Gritsman, William P. Tong, and Joseph R. Bertino: $gamma$ -Glutamyl Hydrolase from Human Sarcoma HT-1080 Cells: Characterization and Inhibition by Glutamine Antagonists
Mol Pharmacol 1997 51: 825-832. [Abstract] [Full Text] [PDF]

Jahanshah Amin, Amy Brooks-Kayal, and David S. Weiss: Two Tyrosine Residues on the $alpha$ Subunit Are Crucial for Benzodiazepine Binding and Allosteric Modulation of $gamma$ -Aminobutyric Acid_A Receptors
Mol Pharmacol 1997 51: 833-841. [Abstract] [Full Text] [PDF]

G. Zanninelli, H. Glickstein, W. Breuer, P. Milgram, P. Brissot, R. C. Hider, A. M. Konijn, J. Libman, A. Shanzer, and Z. Ioav Cabantchik: Chelation and Mobilization of Cellular Iron by Different Classes of Chelators
Mol Pharmacol 1997 51: 842-852. [Abstract] [Full Text] [PDF]

Livia C. Hool, Lisa M. Oleksa, and Robert D. Harvey: Role of G Proteins in $alpha$ ₁-Adrenergic Inhibition of the $beta$ -Adrenergically Activated Chloride Current in Cardiac Myocytes
Mol Pharmacol 1997 51: 853-860. [Abstract] [Full Text] [PDF]

James Chao, Nikolaus Seiler, Jacques Renault, Keiko Kashiwagi, Takashi Masuko, Kazuei Igarashi, and Keith Williams: N¹-Dansyl-Spermine and N¹-(n-Octanesulfonyl)-Spermine, Novel Glutamate Receptor Antagonists: Block and Permeation of N-Methyl-D-Aspartate Receptors
Mol Pharmacol 1997 51: 861-871. [Abstract] [Full Text] [PDF]

Dongming Cai, Jennifer G. Mulle, and David T. Yue: Inhibition of Recombinant Ca²⁺ Channels by Benzothiazepines and Phenylalkylamines: Class-Specific Pharmacology and Underlying Molecular Determinants
Mol Pharmacol 1997 51: 872-881. [Abstract] [Full Text] [PDF]

Hannu Kankaanranta, Richard G. Knowles, Pauli Vuorinen, Outi Kosonen, Päivi Holm, and Eeva Moilanen: 3-Morpholino-Sydnonimine-Induced Suppression of Human Neutrophil Degranulation is Not Mediated by Cyclic GMP, Nitric Oxide or Peroxynitrite: Inhibition of the Increase in Intracellular Free Calcium Concentration by N-Morpholino- iminoacetonitrile, a Metabolite of 3-Morpholino-Sydnonimine
Mol Pharmacol 1997 51: 882-888. [Abstract] [Full Text] [PDF]

Wilma Kuipers, Regina Link, Piet J. Standaar, Axel R. Stoit, Ineke Van Wijngaarden, Rob Leurs, and Adriaan P. Ijzerman: Study of the Interaction Between Aryloxypropanolamines and Asn386 in Helix VII of the Human 5-Hydroxytryptamine_1A Receptor
Mol Pharmacol 1997 51: 889-896. [Abstract] [Full Text] [PDF]

Cover Caption:

About the cover: Stereo view of the proposed interaction between the neuropeptide Y Y₁ receptor and a nonpeptide analog ofthe carboxyl-terminal four amino acids of neuropeptide Y. Thehelices of the human Y₁ receptor are shown in yellow ribbon, andthe side chains of the binding site are shown in yellow. The nonpeptideanalog BIB 3226 is colored by atom type (green, carbon; red, oxygen;blue, nitrogen; white, hydrogen). The model was derived by comparisonof the affinity of neuropeptide Y and BIB 3226 to a large numberof Y₁ receptor mutants expressed in HeLa cells. From Sautel, M.,K. Rudolph, H. Wittneben, H. Herzog, R. Martinez, M. Munoz, W.Eberlein, W. Engel, P. Walker, A. G. Beck-Sickinger. NeuropeptideY and the nonpeptide antagonist BIBP 3226 share an overlappingbinding siteatthe human Y1 receptor. Mol. Pharmacol. 50:285-292(1996).