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Other Issues:
January 1998; 53 (1)   [Index by Author]  [Cover Caption]
       Accelerated Communication
       Articles
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Accelerated Communication:

Tomoyuki Nishizaki, Toshiyuki Matsuoka, Tamotsu Nomura, Katumi Sumikawa, Tadashi Shiotani, Shigeo Watabe, and Mitsunobu Yoshii
Nefiracetam Modulates Acetylcholine Receptor Currents via Two Different Signal Transduction Pathways
Mol Pharmacol 1998 53: 1-5. [Abstract] [Full Text] [PDF]  

Articles:

Christoph Schwarzer, Nikolaus Kofler, and Günther Sperk
Up-Regulation of Neuropeptide Y-Y2 Receptors in an Animal Model of Temporal Lobe Epilepsy
Mol Pharmacol 1998 53: 6-13. [Abstract] [Full Text] [PDF]  

Colin N. A. Palmer, Mei-H. Hsu, Keith J. Griffin, Judy L. Raucy, and Eric F. Johnson
Peroxisome Proliferator Activated Receptor-alpha Expression in Human Liver
Mol Pharmacol 1998 53: 14-22. [Abstract] [Full Text] [PDF]  

Saveria Iona, Margherita Cuomo, Tamara Bushnik, Fabio Naro, Claudio Sette, Martin Hess, Earl R. Shelton, and Marco Conti
Characterization of the Rolipram-Sensitive, Cyclic AMP-Specific Phosphodiesterases: Identification and Differential Expression of Immunologically Distinct Forms in the Rat Brain
Mol Pharmacol 1998 53: 23-32. [Abstract] [Full Text] [PDF]  

Zheng-Hong Qin, Yumei Wang, Masami Nakai, and Thomas N. Chase
Nuclear Factor-kappa B Contributes to Excitotoxin-Induced Apoptosis in Rat Striatum
Mol Pharmacol 1998 53: 33-42. [Abstract] [Full Text] [PDF]  

Hongzu Ren and Gary L. Stiles
A Single-Stranded DNA Binding Site in the Human A1 Adenosine Receptor Gene Promoter
Mol Pharmacol 1998 53: 43-51. [Abstract] [Full Text] [PDF]  

Andrew G. Smith, Bruce Clothier, Susan Robinson, Matthew J. Scullion, Philip Carthew, Richard Edwards, Jinli Luo, Chang Kee Lim, and Michel Toledano
Interaction between Iron Metabolism and 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Mice with Variants of the Ahr Gene: A Hepatic Oxidative Mechanism
Mol Pharmacol 1998 53: 52-61. [Abstract] [Full Text] [PDF]  

Pascal Verdier-Pinard, Jing-Yu Lai, Hae-Dong Yoo, Jurong Yu, Brian Marquez, Dale G. Nagle, Mitch Nambu, James D. White, J. R. Falck, William H. Gerwick, Billy W. Day, and Ernest Hamel
Structure-Activity Analysis of the Interaction of Curacin A, the Potent Colchicine Site Antimitotic Agent, with Tubulin and Effects of Analogs on the Growth of MCF-7 Breast Cancer Cells
Mol Pharmacol 1998 53: 62-76. [Abstract] [Full Text] [PDF]  

Christian Bailly, Pierre Colson, Claude Houssier, Elisabete Rodrigues-Pereira, Michelle Prudhomme, and Michael J. Waring
Recognition of Specific Sequences in DNA by a Topoisomerase I Inhibitor Derived from the Antitumor Drug Rebeccamycin
Mol Pharmacol 1998 53: 77-87. [Abstract] [Full Text] [PDF]  

Guang Jian Wang, Hye Joo Chung, Jamie Schnuer, Kara Pratt, Anthony C. Zable, Michael P. Kavanaugh, and Paul A. Rosenberg
High Affinity Glutamate Transport in Rat Cortical Neurons in Culture
Mol Pharmacol 1998 53: 88-96. [Abstract] [Full Text] [PDF]  

Christoph Schumacher, Catherine L. Cioffi, Haamid Sharif, William Haston, Brett P. Monia, and Lawrence Wennogle
Exposure of Human Vascular Smooth Muscle Cells to Raf-1 Antisense Oligodeoxynucleotides: Cellular Responses and Pharmacodynamic Implications
Mol Pharmacol 1998 53: 97-104. [Abstract] [Full Text] [PDF]  

Alakananda Basu
The Involvement of Novel Protein Kinase C Isozymes in Influencing Sensitivity of Breast Cancer MCF-7 Cells to Tumor Necrosis Factor-alpha
Mol Pharmacol 1998 53: 105-111. [Abstract] [Full Text] [PDF]  

Ashima Saxena, Yacov Ashani, Lily Raveh, David Stevenson, Thakor Patel, and B. P. Doctor
Role of Oligosaccharides in the Pharmacokinetics of Tissue-Derived and Genetically Engineered Cholinesterases
Mol Pharmacol 1998 53: 112-122. [Abstract] [Full Text] [PDF]  

Andreas Friebe and Doris Koesling
Mechanism of YC-1-Induced Activation of Soluble Guanylyl Cyclase
Mol Pharmacol 1998 53: 123-127. [Abstract] [Full Text] [PDF]  

Hideo Kikkawa, Masafumi Isogaya, Taku Nagao, and Hitoshi Kurose
The Role of the Seventh Transmembrane Region in High Affinity Binding of a beta 2-Selective Agonist TA-2005
Mol Pharmacol 1998 53: 128-134. [Abstract] [Full Text] [PDF]  

Tricia D. Levan, John W. Bloom, Deanna G. Adams, Jennifer L. Hensel, and Marilyn Halonen
Platelet-Activating Factor Induction of Activator Protein-1 Signaling in Bronchial Epithelial Cells
Mol Pharmacol 1998 53: 135-140. [Abstract] [Full Text] [PDF]  

C. Marbeuf-Gueye, H. J. Broxterman, F. Dubru, W. Priebe, and A. Garnier-Suillerot
Kinetics of Anthracycline Efflux from Multidrug Resistance Protein-Expressing Cancer Cells Compared with P-Glycoprotein-Expressing Cancer Cells
Mol Pharmacol 1998 53: 141-147. [Abstract] [Full Text] [PDF]  

Kouichiro Minami, Robert W. Gereau IV, Makiko Minami, Stephen F. Heinemann, and R. Adron Harris
Effects of Ethanol and Anesthetics on Type 1 and 5 Metabotropic Glutamate Receptors Expressed in Xenopus laevis Oocytes
Mol Pharmacol 1998 53: 148-156. [Abstract] [Full Text] [PDF]  

Johan Neyts, Jan Balzarini, Graciela Andrei, Zhu Chaoyong, Robert Snoeck, Albert Zimmermann, Thomas Mertens, Anna Karlsson, and Erik De Clercq
Intracellular Metabolism of the N7-Substituted Acyclic Nucleoside Analog 2-Amino-7-(1,3-dihydroxy-2-propoxymethyl)purine, a Potent Inhibitor of Herpesvirus Replication
Mol Pharmacol 1998 53: 157-165. [Abstract] [Full Text] [PDF]  

Birgitte Holst, Sannah Zoffmann, Christian E. Elling, Siv A. Hjorth, and Thue W. Schwartz
Steric Hindrance Mutagenesis versus Alanine Scan in Mapping of Ligand Binding Sites in the Tachykinin NK1 Receptor
Mol Pharmacol 1998 53: 166-175. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: Hypothetical structure of amphotericin B channel in aqueous solution. Left, view from extracellular surface. Green, carbon atoms; red, oxygen atoms; blue, nitrogen atoms; white, hydrogen atoms. Cholesterol molecules are shown in magenta. Right, view from within the membrane as a side projection. The amphotericin B molecule is shown in green, cholesterol in magenta. Water molecules included in the simulation are shown above and below the channel. From Baginski M, Resat H, and McCammon JA (1997) Molecular properties of Amphotericin B membrane channel: A molecular dynamics simulation. Mol. Pharmacol. 52:560-570.



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