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April 1998; 53 (4)   [Index by Author]  [Cover Caption]
       Accelerated Communication
       Articles
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Accelerated Communication:

Paavo Honkakoski, Rick Moore, Kimberly A. Washburn, and Masahiko Negishi
Activation by Diverse Xenochemicals of the 51-Base Pair Phenobarbital-Responsive Enhancer Module in the CYP2B10 Gene
Mol Pharmacol 1998 53: 597-601. [Abstract] [Full Text] [PDF]  

Articles:

Consuelo Gajate, Antonio Santos-Beneit, Manuel Modolell, and Faustino Mollinedo
Involvement of c-Jun NH2-Terminal Kinase Activation and c-Jun in the Induction of Apoptosis by the Ether Phospholipid 1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphocholine
Mol Pharmacol 1998 53: 602-612. [Abstract] [Full Text] [PDF]  

Teresa Palomero, Francisco Barros, Donato del Camino, Cristina G. Viloria, and Pilar de la Peña
A G Protein beta gamma Dimer-Mediated Pathway Contributes to Mitogen-Activated Protein Kinase Activation by Thyrotropin-Releasing Hormone Receptors in Transfected COS-7 Cells
Mol Pharmacol 1998 53: 613-622. [Abstract] [Full Text] [PDF]  

Courtney E. W. Sulentic, Michael P. Holsapple, and Norbert E. Kaminski
Aryl Hydrocarbon Receptor-Dependent Suppression by 2,3,7,8-Tetrachlorodibenzo-p-dioxin of IgM Secretion in Activated B Cells
Mol Pharmacol 1998 53: 623-629. [Abstract] [Full Text] [PDF]  

Huige Li, Silke A. Oehrlein, Thomas Wallerath, Irmgard Ihrig-Biedert, Paulus Wohlfart, Thomas Ulshöfer, Timm Jessen, Thomas Herget, Ulrich Förstermann, and Hartmut Kleinert
Activation of Protein Kinase Calpha and/or epsilon  Enhances Transcription of the Human Endothelial Nitric Oxide Synthase Gene
Mol Pharmacol 1998 53: 630-637. [Abstract] [Full Text] [PDF]  

Qi Chen and Arthur I. Cederbaum
Cytotoxicity and Apoptosis Produced by Cytochrome P450 2E1 in Hep G2 Cells
Mol Pharmacol 1998 53: 638-648. [Abstract] [Full Text] [PDF]  

Dietmar Bengel, Dennis L. Murphy, Anne M. Andrews, Christine H. Wichems, Douglas Feltner, Armin Heils, Rainald Mössner, Heiner Westphal, and Klaus-Peter Lesch
Altered Brain Serotonin Homeostasis and Locomotor Insensitivity to 3,4-Methylenedioxymethamphetamine ("Ecstasy") in Serotonin Transporter-Deficient Mice
Mol Pharmacol 1998 53: 649-655. [Abstract] [Full Text] [PDF]  

Richard J. H. Wojcikiewicz and Su Ge Luo
Differences Among Type I, II, and III Inositol-1,4,5-Trisphosphate Receptors in Ligand-Binding Affinity Influence the Sensitivity of Calcium Stores to Inositol-1,4,5-Trisphosphate
Mol Pharmacol 1998 53: 656-662. [Abstract] [Full Text] [PDF]  

Zhongzhen Nie, Yun Mei, Mary Ford, Leonard Rybak, Adrianna Marcuzzi, Hongzu Ren, Gary L. Stiles, and Vickram Ramkumar
Oxidative Stress Increases A1 Adenosine Receptor Expression by Activating Nuclear Factor kappa B
Mol Pharmacol 1998 53: 663-669. [Abstract] [Full Text] [PDF]  

Alberto J. Kaumann, Frédéric Preitner, Doreen Sarsero, Peter Molenaar, Jean-Pierre Revelli, and Jean Paul Giacobino
(-)-CGP 12177 Causes Cardiostimulation and Binds to Cardiac Putative beta 4-Adrenoceptors in Both Wild-Type and beta 3-Adrenoceptor Knockout Mice
Mol Pharmacol 1998 53: 670-675. [Abstract] [Full Text] [PDF]  

Yanli Ouyang, Seong Gu Hwang, Seung Hyun Han, and Norbert E. Kaminski
Suppression of Interleukin-2 by the Putative Endogenous Cannabinoid 2-Arachidonyl-Glycerol Is Mediated through Down-regulation of the Nuclear Factor of Activated T Cells
Mol Pharmacol 1998 53: 676-683. [Abstract] [Full Text] [PDF]  

Guo-Huang Fan, Jing Zhao, Ya-Lan Wu, Li-Guang Lou, Zhe Zhang, Qing Jing, Lan Ma, and Gang Pei
N-Methyl-D-Aspartate Attenuates Opioid Receptor-Mediated G Protein Activation and This Process Involves Protein Kinase C
Mol Pharmacol 1998 53: 684-690. [Abstract] [Full Text] [PDF]  

William Peter Long, Marilyn Pray-Grant, Jo Chao Tsai, and Gary H. Perdew
Protein Kinase C Activity Is Required for Aryl Hydrocarbon Receptor Pathway-Mediated Signal Transduction
Mol Pharmacol 1998 53: 691-700. [Abstract] [Full Text] [PDF]  

Ryoichi Ishitani, Masaharu Tanaka, Katsuyoshi Sunaga, Nobuo Katsube, and De-Maw Chuang
Nuclear Localization of Overexpressed Glyceraldehyde-3-Phosphate Dehydrogenase in Cultured Cerebellar Neurons Undergoing Apoptosis
Mol Pharmacol 1998 53: 701-707. [Abstract] [Full Text] [PDF]  

Charles V. Preuss, Thomas C. Wood, Carol L. Szumlanski, Rebecca B. Raftogianis, Diane M. Otterness, Blanka Girard, Mary C. Scott, and Richard M. Weinshilboum
Human Histamine N-Methyltransferase Pharmacogenetics: Common Genetic Polymorphisms that Alter Activity
Mol Pharmacol 1998 53: 708-717. [Abstract] [Full Text] [PDF]  

Chunyuan Luo, Yacov Ashani, and Bhupendra P. Doctor
Acceleration of Oxime-Induced Reactivation of Organophosphate-Inhibited Fetal Bovine Serum Acetylcholinesterase by Monoquaternary and Bisquaternary Ligands
Mol Pharmacol 1998 53: 718-726. [Abstract] [Full Text] [PDF]  

Béatrice Hechler, Paul Vigne, Catherine Léon, Jean-Philippe Breittmayer, Christian Gachet, and Christian Frelin
ATP Derivatives Are Antagonists of the P2Y1 Receptor: Similarities to the Platelet ADP Receptor
Mol Pharmacol 1998 53: 727-733. [Abstract] [Full Text] [PDF]  

Laszlo Tretter, Christos Chinopoulos, and Vera Adam-Vizi
Plasma Membrane Depolarization and Disturbed Na+ Homeostasis Induced by the Protonophore Carbonyl Cyanide-p-trifluoromethoxyphenyl-hydrazon in Isolated Nerve Terminals
Mol Pharmacol 1998 53: 734-741. [Abstract] [Full Text] [PDF]  

Kari R. Hoyt, Stuart R. Arden, Elias Aizenman, and Ian J. Reynolds
Reverse Na+/Ca2+ Exchange Contributes to Glutamate-Induced Intracellular Ca2+ Concentration Increases in Cultured Rat Forebrain Neurons
Mol Pharmacol 1998 53: 742-749. [Abstract] [Full Text] [PDF]  

Valérie Capra, Simonetta Nicosia, Daniela Ragnini, Maurizio Mezzetti, Dietrich Keppler, and G. Enrico Rovati
Identification and Characterization of Two Cysteinyl-Leukotriene High Affinity Binding Sites with Receptor Characteristics in Human Lung Parenchyma
Mol Pharmacol 1998 53: 750-758. [Abstract] [Full Text] [PDF]  

Philip G. Szekeres, Jennifer A. Koenig, and J. Michael Edwardson
The Relationship between Agonist Intrinsic Activity and the Rate of Endocytosis of Muscarinic Receptors in a Human Neuroblastoma Cell Line
Mol Pharmacol 1998 53: 759-765. [Abstract] [Full Text] [PDF]  

James E. Porter, Stephanie E. Edelmann, David J. Waugh, Michael T. Piascik, and Dianne M. Perez
The Agonism and Synergistic Potentiation of Weak Partial Agonists by Triethylamine in alpha 1-Adrenergic Receptor Activation: Evidence for a Salt Bridge as the Initiating Process
Mol Pharmacol 1998 53: 766-771. [Abstract] [Full Text] [PDF]  

Fan Meng, Yasuko Ueda, Mary T. Hoversten, Larry P. Taylor, Rainer K. Reinscheid, Frederick J. Monsma, Stanley J. Watson, Olivier Civelli, and Huda Akil
Creating a Functional Opioid Alkaloid Binding Site in the Orphanin FQ Receptor through Site-Directed Mutagenesis
Mol Pharmacol 1998 53: 772-777. [Abstract] [Full Text] [PDF]  

Marie-Laure Parmentier, Cécile Joly, Sophie Restituito, Joël Bockaert, Yves Grau, and Jean-Philippe Pin
The G Protein-Coupling Profile of Metabotropic Glutamate Receptors, as Determined with Exogenous G Proteins, Is Independent of Their Ligand Recognition Domain
Mol Pharmacol 1998 53: 778-786. [Abstract] [Full Text] [PDF]  

Naoya Sugiyama, Pascale Marchot, Chiaki Kawanishi, Hitoshi Osaka, Brian Molles, Steven M. Sine, and Palmer Taylor
Residues at the Subunit Interfaces of the Nicotinic Acetylcholine Receptor That Contribute to alpha -Conotoxin M1 Binding
Mol Pharmacol 1998 53: 787-794. [Abstract] [Full Text] [PDF]  

Silvia Pfeiffer, Astrid Schrammel, Doris Koesling, Kurt Schmidt, and Bernd Mayer
Molecular Actions of a Mn(III)Porphyrin Superoxide Dismutase Mimetic and Peroxynitrite Scavenger: Reaction with Nitric Oxide and Direct Inhibition of NO Synthase and Soluble Guanylyl Cyclase
Mol Pharmacol 1998 53: 795-800. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: Hypothetical structure of amphotericin B channel in aqueous solution. Left, view from extracellular surface. Green, carbon atoms; red, oxygen atoms; blue, nitrogen atoms; white, hydrogen atoms. Cholesterol molecules are shown in magenta. Right, view from within the membrane as a side projection. The amphotericin B molecule is shown in green, cholesterol in magenta. Water molecules included in the simulation are shown above and below the channel. From Baginski M, Resat H, and McCammon JA (1997) Molecular properties of Amphotericin B membrane channel: A molecular dynamics simulation. Mol. Pharmacol. 52:560-570.



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