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May 1998; 53 (5)   [Index by Author]  [Cover Caption]
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Articles:

Marina Kukhanova, Xiuyan Li, Shu-Hui Chen, Ivan King, Terrence Doyle, William Prusoff, and Yung-Chi Cheng
Interaction of beta -L-2',3'-dideoxy-2',3'-didehydro-5-fluoro-CTP with Human Immunodeficiency Virus-1 Reverse Transcriptase and Human DNA Polymerases: Implications for Human Immunodeficiency Virus Drug Design
Mol Pharmacol 1998 53: 801-807. [Abstract] [Full Text] [PDF]  

Maria Waldhoer, Elisa Bofill-Cardona, Graeme Milligan, Michael Freissmuth, and Christian Nanoff
Differential Uncoupling of A1 Adenosine and D2 Dopamine Receptors by Suramin and Didemethylated Suramin (NF037)
Mol Pharmacol 1998 53: 808-818. [Abstract] [Full Text] [PDF]  

Neil A. Jones, Jonathon Turner, Amanda J. McIlwrath, Robert Brown, and Caroline Dive
Cisplatin- and Paclitaxel-Induced Apoptosis of Ovarian Carcinoma Cells and the Relationship between Bax and Bak Up-Regulation and the Functional Status of p53
Mol Pharmacol 1998 53: 819-826. [Abstract] [Full Text] [PDF]  

Scott D. Sorensen, Daniel A. Linseman, Edward L. McEwen, Anne M. Heacock, and Stephen K. Fisher
A Role for a Wortmannin-Sensitive Phosphatidylinositol-4-Kinase in the Endocytosis of Muscarinic Cholinergic Receptors
Mol Pharmacol 1998 53: 827-836. [Abstract] [Full Text] [PDF]  

M. Haslauer, K. Baltensperger, and H. Porzig
Thrombin and Phorbol Esters Potentiate Gs-Mediated cAMP Formation in Intact Human Erythroid Progenitors via Two Synergistic Signaling Pathways Converging on Adenylyl Cyclase Type VII
Mol Pharmacol 1998 53: 837-845. [Abstract] [Full Text] [PDF]  

Zdenka Balcarová, Jana Kaspárková, Alena Zákovská, Olga Nováková, Maria F. Sivo, Giovanni Natile, and Viktor Brabec
DNA Interactions of a Novel Platinum Drug, cis-[PtCl(NH3)2(N7-Acyclovir)]+
Mol Pharmacol 1998 53: 846-855. [Abstract] [Full Text] [PDF]  

James G. Granneman, Kristine N. Lahners, and Ying Zhai
Agonist Interactions with Chimeric and Mutant beta 1- and beta 3-Adrenergic Receptors: Involvement of the Seventh Transmembrane Region in Conferring Subtype Specificity
Mol Pharmacol 1998 53: 856-861. [Abstract] [Full Text] [PDF]  

Herbert M. Himmel, Dagmar Meyer zu Heringdorf, Bernd Windorfer, Chris J. van Koppen, Ursula Ravens, and Karl H. Jakobs
Guanine Nucleotide-Sensitive Inhibition of L-Type Ca2+ Current by Lysosphingolipids in RINm5F Insulinoma Cells
Mol Pharmacol 1998 53: 862-869. [Abstract] [Full Text] [PDF]  

Jeffrey Horenstein and Myles H. Akabas
Location of a High Affinity Zn2+ Binding Site in the Channel of alpha 1beta 1 gamma -Aminobutyric AcidA Receptors
Mol Pharmacol 1998 53: 870-877. [Abstract] [Full Text] [PDF]  

Alexandre Jagerschmidt, Nathalie Guillaume, Bernard P. Roques, and Florence Noble
Binding Sites and Transduction Process of the CholecystokininB Receptor: Involvement of Highly Conserved Aromatic Residues of the Transmembrane Domains Evidenced by Site-Directed Mutagenesis
Mol Pharmacol 1998 53: 878-885. [Abstract] [Full Text] [PDF]  

John C. Shryock, Mark J. Ozeck, and Luiz Belardinelli
Inverse Agonists and Neutral Antagonists of Recombinant Human A1 Adenosine Receptors Stably Expressed in Chinese Hamster Ovary Cells
Mol Pharmacol 1998 53: 886-893. [Abstract] [Full Text] [PDF]  

Shinji Kosugi, Toru Mori, and Andrew Shenker
An Anionic Residue at Position 564 Is Important for Maintaining the Inactive Conformation of the Human Lutropin/Choriogonadotropin Receptor
Mol Pharmacol 1998 53: 894-901. [Abstract] [Full Text] [PDF]  

Hai Hu and Eduardo Marban
Isoform-Specific Inhibition of L-Type Calcium Channels by Dihydropyridines Is Independent of Isoform-Specific Gating Properties
Mol Pharmacol 1998 53: 902-907. [Abstract] [Full Text] [PDF]  

Sharon Lobert, Jeffrey W. Ingram, Bridget T. Hill, and John J. Correia
A Comparison of Thermodynamic Parameters for Vinorelbine- and Vinflunine-Induced Tubulin Self-Association by Sedimentation Velocity
Mol Pharmacol 1998 53: 908-915. [Abstract] [Full Text] [PDF]  

Ray A. Leppik, Sebastian Lazareno, Anita Mynett, and Nigel J. M. Birdsall
Characterization of the Allosteric Interactions between Antagonists and Amiloride Analogues at the Human alpha 2A-Adrenergic Receptor
Mol Pharmacol 1998 53: 916-925. [Abstract] [Full Text] [PDF]  

Vandana Balasubramanian, Linh T. Nguyen, Sathyamangalam V. Balasubramanian, and Murali Ramanathan
Interferon-gamma -Inhibitory Oligodeoxynucleotides Alter the Conformation of Interferon-gamma
Mol Pharmacol 1998 53: 926-932. [Abstract] [Full Text] [PDF]  

Keith Williams, Albert J. Pahk, Keiko Kashiwagi, Takashi Masuko, Nguyen D. Nguyen, and Kazuei Igarashi
The Selectivity Filter of the N-Methyl-D-Aspartate Receptor: A Tryptophan Residue Controls Block and Permeation of Mg2+
Mol Pharmacol 1998 53: 933-941. [Abstract] [Full Text] [PDF]  

Geoffrey T. Swanson, Tim Green, and Stephen F. Heinemann
Kainate Receptors Exhibit Differential Sensitivities to (S)-5-Iodowillardiine
Mol Pharmacol 1998 53: 942-949. [Abstract] [Full Text] [PDF]  

Paul Whiteaker, Christopher G. V. Sharples, and Susan Wonnacott
Agonist-Induced Up-Regulation of alpha 4beta 2 Nicotinic Acetylcholine Receptors in M10 Cells: Pharmacological and Spatial Definition
Mol Pharmacol 1998 53: 950-962. [Abstract] [Full Text] [PDF]  

Christian C. Jansson, Jyrki P. Kukkonen, Johnny Näsman, Ge Huifang, Siegfried Wurster, Raimo Virtanen, Juha-Matti Savola, Vic Cockcroft, and Karl E. O. Åkerman
Protean Agonism at alpha 2A-Adrenoceptors
Mol Pharmacol 1998 53: 963-968. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: Hypothetical structure of amphotericin B channel in aqueous solution. Left, view from extracellular surface. Green, carbon atoms; red, oxygen atoms; blue, nitrogen atoms; white, hydrogen atoms. Cholesterol molecules are shown in magenta. Right, view from within the membrane as a side projection. The amphotericin B molecule is shown in green, cholesterol in magenta. Water molecules included in the simulation are shown above and below the channel. From Baginski M, Resat H, and McCammon JA (1997) Molecular properties of Amphotericin B membrane channel: A molecular dynamics simulation. Mol. Pharmacol. 52:560-570.



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