Mol Pharm -- Table of Contents (53 [6])

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June 1998; 53 (6)   [Index by Author] [Cover Caption]

       Accelerated Communication

       Articles

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Accelerated Communication:

Caterina Virginio, Graeme Robertson, Annmarie Surprenant, and R. Alan North: Trinitrophenyl-Substituted Nucleotides Are Potent Antagonists Selective for P2X₁, P2X₃, and Heteromeric P2X_2/3 Receptors
Mol Pharmacol 1998 53: 969-973. [Abstract] [Full Text] [PDF]

Tsung-I Peng and J. Timothy Greenamyre: Privileged Access to Mitochondria of Calcium Influx through N-Methyl-D-Aspartate Receptors
Mol Pharmacol 1998 53: 974-980. [Abstract] [Full Text] [PDF]

Articles:

Stephen R. Marsh, Galina Grishina, Paul T. Wilson, and Catherine H. Berlot: Receptor-Mediated Activation of G_s: Evidence for Intramolecular Signal Transduction
Mol Pharmacol 1998 53: 981-990. [Abstract] [Full Text] [PDF]

Iain Gardner, Nasir Zahid, Duncan MacCrimmon, and Jack P. Uetrecht: A Comparison of the Oxidation of Clozapine and Olanzapine to Reactive Metabolites and the Toxicity of these Metabolites to Human Leukocytes
Mol Pharmacol 1998 53: 991-998. [Abstract] [Full Text] [PDF]

Iain Gardner, J. Steven Leeder, Terrence Chin, Nasir Zahid, and Jack P. Uetrecht: A Comparison of the Covalent Binding of Clozapine and Olanzapine to Human Neutrophils In Vitro and In Vivo
Mol Pharmacol 1998 53: 999-1008. [Abstract] [Full Text] [PDF]

Fabien Schmidlin, Didier Scherrer, Laurent Daeffler, Claude Bertrand, Yves Landry, and Jean-Pierre Gies: Interleukin-1 $beta$ Induces Bradykinin B₂ Receptor Gene Expression through a Prostanoid Cyclic AMP-Dependent Pathway in Human Bronchial Smooth Muscle Cells
Mol Pharmacol 1998 53: 1009-1015. [Abstract] [Full Text] [PDF]

K. Cameron Falkner, Thomas H. Rushmore, Mark W. Linder, and Russell A. Prough: Negative Regulation of the Rat Glutathione S-Transferase A2 Gene by Glucocorticoids Involves a Canonical Glucocorticoid Consensus Sequence
Mol Pharmacol 1998 53: 1016-1026. [Abstract] [Full Text] [PDF]

Antony J. Hansen, Ying-Hue Lee, Esta Sterneck, Frank J. Gonzalez, and Peter I. Mackenzie: C/EBP $alpha$ Is a Regulator of the UDP Glucuronosyltransferase UGT2B1 Gene
Mol Pharmacol 1998 53: 1027-1033. [Abstract] [Full Text] [PDF]

Pedro J. Gonzalez-Cabrera, Patrick L. Iversen, Marvin F. Liu, Margaret A. Scofield, and William B. Jeffries: Selective Inhibition of $alpha$ _1B-Adrenergic Receptor Expression and Function Using a Phosphorothioate Antisense Oligodeoxynucleotide
Mol Pharmacol 1998 53: 1034-1039. [Abstract] [Full Text] [PDF]

M. S. Rhee, B. Lindau-Shepard, K. J. Chave, J. Galivan, and T. J. Ryan: Characterization of Human Cellular $gamma$ -Glutamyl Hydrolase
Mol Pharmacol 1998 53: 1040-1046. [Abstract] [Full Text] [PDF]

Derek Strassheim, Ping-Yee Law, and Horace H. Loh: Contribution of Phospholipase C- $beta$ 3 Phosphorylation to the Rapid Attenuation of Opioid-Activated Phosphoinositide Response
Mol Pharmacol 1998 53: 1047-1053. [Abstract] [Full Text] [PDF]

Chuan-Chang Chuang, Sai-Koong Tan, Lung-Kuo Tai, Jin-Ping Hsin, and Fung-Fang Wang: Evidence for the Involvement of Protein Kinase C in the Inhibition of Prolactin Gene Expression by Transforming Growth Factor- $beta$ ₂
Mol Pharmacol 1998 53: 1054-1061. [Abstract] [Full Text] [PDF]

Rémon A. M. H. van Aubel, Marcel A. van Kuijck, Jan B. Koenderink, Peter M. T. Deen, Carel H. van Os, and Frans G. M. Russel: Adenosine Triphosphate-Dependent Transport of Anionic Conjugates by the Rabbit Multidrug Resistance-Associated Protein Mrp2 Expressed in Insect Cells
Mol Pharmacol 1998 53: 1062-1067. [Abstract] [Full Text] [PDF]

Tomoko Hirohashi, Hiroshi Suzuki, Kousei Ito, Kotaro Ogawa, Kazuhiko Kume, Takao Shimizu, and Yuichi Sugiyama: Hepatic Expression of Multidrug Resistance-Associated Protein-Like Proteins Maintained in Eisai Hyperbilirubinemic Rats
Mol Pharmacol 1998 53: 1068-1075. [Abstract] [Full Text] [PDF]

Sjef J. De Kimpe, Erik E. Änggård, and Martin J. Carrier: Reactive Oxygen Species Regulate Macrophage Scavenger Receptor Type I, but Not Type II, in the Human Monocytic Cell Line THP-1
Mol Pharmacol 1998 53: 1076-1082. [Abstract] [Full Text] [PDF]

Lance G. Hammerland, James E. Garrett, Benjamin C. P. Hung, Cynthia Levinthal, and Edward F. Nemeth: Allosteric Activation of the Ca²⁺ Receptor Expressed in Xenopus laevis Oocytes by NPS 467 or NPS 568
Mol Pharmacol 1998 53: 1083-1088. [Abstract] [Full Text] [PDF]

Margarita Ioannou, Charalambos Coutsogeorgopoulos, and Dennis Synetos: Kinetics of Inhibition of Rabbit Reticulocyte Peptidyltransferase by Anisomycin and Sparsomycin
Mol Pharmacol 1998 53: 1089-1096. [Abstract] [Full Text] [PDF]

Masanori Baba, Mika Okamoto, Masaki Kawamura, Masahiko Makino, Tomoe Higashida, Tohru Takashi, Youichi Kimura, Tohru Ikeuchi, Toshifumi Tetsuka, and Takashi Okamoto: Inhibition of Human Immunodeficiency Virus Type 1 Replication and Cytokine Production by Fluoroquinoline Derivatives
Mol Pharmacol 1998 53: 1097-1103. [Abstract] [Full Text] [PDF]

Christophe Arnoult, Michel Villaz, and Harvey M. Florman: Pharmacological Properties of the T-Type Ca²⁺ Current of Mouse Spermatogenic Cells
Mol Pharmacol 1998 53: 1104-1111. [Abstract] [Full Text] [PDF]

Charles W. Luetje, Floyd N. Maddox, and Scott C. Harvey: Glycosylation within the Cysteine Loop and Six Residues Near Conserved Cys192/Cys193 Are Determinants of Neuronal Bungarotoxin Sensitivity on the Neuronal Nicotinic Receptor $alpha$ 3 Subunit
Mol Pharmacol 1998 53: 1112-1119. [Abstract] [Full Text] [PDF]

Arthur Christopoulos, Tracie L. Pierce, Jennifer L. Sorman, and Esam E. El-Fakahany: On the Unique Binding and Activating Properties of Xanomeline at the M₁ Muscarinic Acetylcholine Receptor
Mol Pharmacol 1998 53: 1120-1130. [Abstract] [Full Text] [PDF]

Irmgard Wiesenberg, Michele Chiesi, Martin Missbach, Carsten Spanka, Werner Pignat, and Carsten Carlberg: Specific Activation of the Nuclear Receptors PPAR $gamma$ and RORA by the Antidiabetic Thiazolidinedione BRL 49653 and the Antiarthritic Thiazolidinedione Derivative CGP 52608
Mol Pharmacol 1998 53: 1131-1138. [Abstract] [Full Text] [PDF]

Martina Schmidt, Barbara Lohmann, Kerstin Hammer, Stephan Haupenthal, Matthias Voß, Christoph Nehls, and Karl H. Jakobs: G_i- and Protein Kinase C-Mediated Heterologous Potentiation of Phospholipase C Signaling by G Protein-Coupled Receptors
Mol Pharmacol 1998 53: 1139-1148. [Abstract] [Full Text] [PDF]

Cover Caption:

About the cover: Hypothetical structure of amphotericin B channel in aqueous solution. Left, view from extracellular surface.Green, carbon atoms; red, oxygen atoms; blue, nitrogen atoms;white, hydrogen atoms. Cholesterol molecules are shown in magenta.Right, view from within the membrane as a side projection. Theamphotericin B molecule is shown in green, cholesterol in magenta.Water molecules included in the simulation are shown above andbelow the channel. From Baginski M, Resat H, and McCammon JA (1997)Molecular properties of Amphotericin B membrane channel: A moleculardynamics simulation. Mol. Pharmacol. 52:560-570.