Mol Pharm -- Table of Contents (54 [3])

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September 1998; 54 (3)   [Index by Author] [Cover Caption]

       Accelerated Communication

       Articles

       Errata

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Accelerated Communication:

Xuechu Zhen, Kunihiro Uryu, Hoau-Yan Wang, and Eitan Friedman: D₁ Dopamine Receptor Agonists Mediate Activation of p38 Mitogen-Activated Protein Kinase and c-Jun Amino-Terminal Kinase by a Protein Kinase A-Dependent Mechanism in SK-N-MC Human Neuroblastoma Cells
Mol Pharmacol 1998 54: 453-458. [Abstract] [Full Text] [PDF]

Articles:

Maoxing Shen and Stanley A. Thayer: Cannabinoid Receptor Agonists Protect Cultured Rat Hippocampal Neurons from Excitotoxicity
Mol Pharmacol 1998 54: 459-462. [Abstract] [Full Text] [PDF]

J. Christopher Corton, Li-Qun Fan, Sherri Brown, Steven P. Anderson, Carlos Bocos, Russell C. Cattley, Agneta Mode, and Jan-Åke Gustafsson: Down-Regulation of Cytochrome P450 2C Family Members and Positive Acute-Phase Response Gene Expression by Peroxisome Proliferator Chemicals
Mol Pharmacol 1998 54: 463-473. [Abstract] [Full Text] [PDF]

Thomas A. Kocarek, Janice M. Kraniak, and Anita B. Reddy: Regulation of Rat Hepatic Cytochrome P450 Expression by Sterol Biosynthesis Inhibition: Inhibitors of Squalene Synthase Are Potent Inducers of CYP2B Expression in Primary Cultured Rat Hepatocytes and Rat Liver
Mol Pharmacol 1998 54: 474-484. [Abstract] [Full Text] [PDF]

Susan M. Sromek and T. Kendall Harden: Agonist-Induced Internalization of the P2Y₂ Receptor
Mol Pharmacol 1998 54: 485-494. [Abstract] [Full Text] [PDF]

Jingshan Chen, Max B. Kelz, Guoqi Zeng, Norio Sakai, Cathy Steffen, Penny E. Shockett, Marina R. Picciotto, Ronald S. Duman, and Eric J. Nestler: Transgenic Animals with Inducible, Targeted Gene Expression in Brain
Mol Pharmacol 1998 54: 495-503. [Abstract] [Full Text] [PDF]

Wei Qu, Richard A. Rippe, Jixiang Ma, Paula Scarborough, Christine Biagini, Fred T. Fiedorek, Gregory S. Travlos, Carol Parker, and Darryl C. Zeldin: Nutritional Status Modulates Rat Liver Cytochrome P450 Arachidonic Acid Metabolism
Mol Pharmacol 1998 54: 504-513. [Abstract] [Full Text] [PDF]

Xiaofei Wang and T. J. Murphy: Inhibition of Cyclic AMP-Dependent Kinase by Expression of a Protein Kinase Inhibitor/Enhanced Green Fluorescent Fusion Protein Attenuates Angiotensin II-Induced Type 1 AT₁ Receptor mRNA Down-Regulation in Vascular Smooth Muscle Cells
Mol Pharmacol 1998 54: 514-524. [Abstract] [Full Text] [PDF]

Ralf Schülein, Ricardo Hermosilla, Alexander Oksche, Marcel Dehe, Burkhard Wiesner, Gerd Krause, and Walter Rosenthal: A Dileucine Sequence and an Upstream Glutamate Residue in the Intracellular Carboxyl Terminus of the Vasopressin V₂ Receptor Are Essential for Cell Surface Transport in COS.M6 Cells
Mol Pharmacol 1998 54: 525-535. [Abstract] [Full Text] [PDF]

Katja C. Zimmermann, Mario Sarbia, Karsten Schrör, and Artur-Aron Weber: Constitutive Cyclooxygenase-2 Expression in Healthy Human and Rabbit Gastric Mucosa
Mol Pharmacol 1998 54: 536-540. [Abstract] [Full Text] [PDF]

Qing Li, Melanie Olesky, R. Kyle Palmer, T. Kendall Harden, and Robert A. Nicholas: Evidence that the p2y3 Receptor Is the Avian Homologue of the Mammalian P2Y₆ Receptor
Mol Pharmacol 1998 54: 541-546. [Abstract] [Full Text] [PDF]

Philip Lazarovici, Hao Jiang, and Donald Fink Jr.: The 38-Amino-Acid Form of Pituitary Adenylate Cyclase-Activating Polypeptide Induces Neurite Outgrowth in PC12 Cells that Is Dependent on Protein Kinase C and Extracellular Signal-Regulated Kinase but not on Protein Kinase A, Nerve Growth Factor Receptor Tyrosine Kinase, p21^ras G protein, and pp60^c-src Cytoplasmic Tyrosine Kinase
Mol Pharmacol 1998 54: 547-558. [Abstract] [Full Text] [PDF]

Yasunori M. Nakashima, Slobodan M. Todorovic, Douglas F. Covey, and Christopher J. Lingle: The Anesthetic Steroid (+)-3 $alpha$ -Hydroxy-5 $alpha$ -androstane-17 $beta$ -carbonitrile Blocks N-, Q-, and R-Type, but Not L- and P-Type, High Voltage-Activated Ca²⁺ Current in Hippocampal and Dorsal Root Ganglion Neurons of the Rat
Mol Pharmacol 1998 54: 559-568. [Abstract] [Full Text] [PDF]

Markus Björklund, Jouni Sirviö, Jukka Puoliväli, Jukka Sallinen, Pekka Jäkälä, Mika Scheinin, Brian K. Kobilka, and Paavo Riekkinen Jr.: $alpha$ _2C-Adrenoceptor-Overexpressing Mice Are Impaired in Executing Nonspatial and Spatial Escape Strategies
Mol Pharmacol 1998 54: 569-576. [Abstract] [Full Text] [PDF]

Frank G. Boess, Claus Riemer, Michael Bös, Jane Bentley, Anne Bourson, and Andrew J. Sleight: The 5-Hydroxytryptamine₆ Receptor-Selective radioligand [³H]Ro 63-0563 Labels 5-Hydroxytryptamine Receptor Binding Sites in Rat and Porcine Striatum
Mol Pharmacol 1998 54: 577-583. [Abstract] [Full Text] [PDF]

Karen M. Kedzie, John E. Donello, Heather A. Krauss, John W. Regan, and Daniel W. Gil: A Single Amino-Acid Substitution in the EP₂ Prostaglandin Receptor Confers Responsiveness to Prostacyclin Analogs
Mol Pharmacol 1998 54: 584-590. [Abstract] [Full Text] [PDF]

Fabian F. Moebius, Raphael J. Reiter, Katrin Bermoser, Hartmut Glossmann, Sang Yun Cho, and Young-Ki Paik: Pharmacological Analysis of Sterol $Delta$ 8- $Delta$ 7 Isomerase Proteins with [³H]Ifenprodil
Mol Pharmacol 1998 54: 591-598. [Abstract] [Full Text] [PDF]

Errata:

: Correction for vol. 44, p. 1016
Mol Pharmacol 1998 54: 599. [Full Text] [PDF]

Cover Caption:

About the cover: Simultaneous monitoring of cytosolic and mitochondrial calcium transients in a cultured striatal neuron.The cell was loaded with calcium green-1N/AM to follow cytosoliccalcium (diffuse green signal) and with rhod-2/AM to follow mitochondrialcalcium (punctate red signal). Laser scanning confocal microscopywas used to measure changes in the two fluorescence signals afterdepolarization with KCl. The graph shows that with this stimulus,cytosolic calcium (green trace) rises rapidly and is followedby a latency of a few seconds caused by mitochondrial calciumaccumulation (red trace). From Peng T-I, Greenamyre JT (1998)Privileged access to mitochondria of calcium influx through N-methyl-D-aspartatereceptors. Mol Pharmacol 53:974-980.